1. We Still Don’t Know Everything about the Lac Operon (But We are Getting Closer!) Steve Brewer Patrick Ehrman Allen Koop

2. Lac Operon

3. Lac Promoter

8. Comparison of No ligand-bound Repressor to DNA-bound and Inducer-bound Repressor 1LBI no ligand; 1LBH inducer; 1LBG DNA

9. Comparison of Inducer-bound Repressor to DNA-bound and No ligand-bound Repressor 1LBH-inducer; 1LBG-DNA; 1LBI no ligand

10. Acknowledgements Slides 2-3 http://users.rcn.com/jkimball.ma.ultranet/Bi ologyPages/L/LacOperon.html http://users.rcn.com/jkimball.ma.ultranet/Bi ologyPages/L/LacOperon.html Slides 4-6, 8-9 NCBI structural program http://www.ncbi.nlm.nih.gov/ Slide 7 http://www.webbooks.com/MoBio/Free/Ch 4D3.htm