Presentation on theme: "Prime AGE Defense™ Formula"— Presentation transcript:
1 Prime AGE Defense™ Formula Market AmericaConvention 2009Presented by: Jan DeBenedetto
2 Disclaimer This presentation has not been evaluated by the Food and Drug Administration.These products are not intended todiagnose, treat, cure, or prevent any disease.
3 What are AGEs? Overview Advanced Glycation Endproducts Chronic high levels of AGEs are proven to accelerate the aging processThey are a diverse group of highly reactive substancesIn excess can wreak havoc in the bodyMany AGEs are sugar derived aldehydes (glyoxals)They can cause generalized cellular dysfunctioni.e. they can affect the entire body!Also known as Glycotoxins
4 AGEs - NaturallyAGEs are produced naturally in normal metabolism and the body can handle low levels of AGEsAGEs are consumed at a moderate level as part of a reasonably good dietThe problems occur due to the chronic overproduction and over consumption of AGEs as well as cigarette smoking
5 NOTHING IN BIOLOGY MAKES SENSE EXCEPT IN THE LIGHT OF EVOLUTION Theodosius Dobzhansky -- Russian evolutionary biologist
6 Historical Perspective of AGEs Our current genome evolved onA low sugar dietA low saturated fat dietA high fiber dietAn alkaline dietA nutrient dense dietA chemical / drug free dietOur current genome evolved in a physically active humanBut what do we do?Eat a high sugar dietEat a high sat fat dietEat a low fiber dietEat a chronic low acid dietEat lots of empty caloriesEat processed and fake foods, lots of Rx & OTCsWe are much less active than our ancestors
7 Historical Perspective - 2 Only within the last 200 years (a blip on the genetic radar screen) did we have simple sugars so readily availableMostly during the last 50 yearsWe are dissonant with our genome and that ain’t a good thing.Don’t mess with Mother Nature…
8 AGEs Can Affect the Following: Oxidative StressCollagen cross-linkingWrinkles and stiffnessMitochondrial functionCellular powerhousesKidney functionGenetic transcription proteins
9 AGEs and arteriesNormal diet arteryLow AGE diet artery
12 Excess AGEs Inside and Out The body can make AGEsExcess carbsExcess sugarChronic stressFood AGEsFoods cooked at high temperatures and for a long timeFrying, grilling, roasting and broilingEspecially in presence of sugars Foods that are cooked until brownBrowning reaction or Maillard reaction generates AGEsCarbonated non-diet beveragesProcessed foodsCigarette smokingAdd AGEs to the long list of cigarette toxins
13 Why haven’t we hearing more about AGEs? The research is relatively new dating back to the late ’80’s.Most scientific publications are from this millenniaOut of 2373 Medline scientific literature citations, 85% are from after the year 2000!RationaleIndustry lobby efforts that negatively influenced research fundingNo major Pharma companies with Rx to address issue.
14 AGEs and AgingThe degree of Glycation of a cell is used as recognition signal of senescent (old/aged) targets for excretion or catabolism.In other words in many cases otherwise healthy cells are tagged and removed due to their being glycated and therefore will not divide into new cells.
15 Smoking and AGEsAGE accumulation in the cornea of NonSmokers (NS) and Smokers (S)
16 AGEs in the bodyGlycation leads to a large and diverse range of chemical speciesThis makes them deleterious to a variety of tissuesThis also makes it difficult to commercially measure AGEs at this point in timeMeasuring HbA1c is a good indicatorGlycated Hemoglobin
18 Dietary AGEsStudyon 4 week “Low AGE” diet => decreased LDL by 28%!on “High AGE” diet LDL increased by 50%!6 week High AGE dietIncreased LDL 33%CRP increased 35%6 week Low AGE dietDecreased LDL 32%CRP decreased 20%
19 Dietary AGEs - 2 Rat study with two groups, The “High AGE” diet rats had higher insulin resistance, oxidative stress, inflammation renal and CV damage and lower glutathione.The group with 50% reduced AGE diet lived significantly longer than the other group (~21%) and with lower inflammatory markers.
20 Prime™ AGE Defense To the Rescue! Supplement FactsServing Size: 3 tabletsServings Per Container: 30Amount Per Serving% Daily ValueThiamine (as Benfotiamine)55 mg4583%Taurine1,000 mg*N-acetylcysteine200 mgAmerican ginseng root extract (5% ginsenosides)500 mgCinnamon bark extract250 mg* Daily value not established.
21 Benfotiamine A lipid soluble form of Thiamine This allows for greater absorption than commercial thiamine and thus higher blood levelSupports the body’s normal ability to remove AGEsProtects endothelium (an active, vital thin layer of cells that line blood vessels) against AGEs
22 American Ginseng Panax quinquefolius Promotes normal serum levels of glucosePowerful AdaptogenActive components are ginsenosides Rb1, Rd and RePromotes normal levels of carboxymethyl-lysine (CML) and its receptors for (AGE) in kidney
23 Cinnamon Bark Extract Promotes healthy metabolism of glucose Helps maintain normal insulin sensitivityStrong antioxidant
24 N-AcetylcysteineSulfur rich antioxidant that is a powerful antioxidantPromotes healthy glutathione levelsGlutathione is one of the body’s natural AGE scavengersHelps maintain normal levels of CML (an AGE)Supports a healthy liver and kidneys
25 Taurine A sulfhydryl derivative of an amino acid Found in abundance in slow twitch (endurance) muscle fibersTaurine levels are typically lower with aging and vegan dietsHas numerous other healthful functions
26 Who can benefit most from Prime™ AGE Defense? SmokersIndividuals who want to age wellIf you indulge your sweet toothEating and drinkingEat lots of Grilled, Broiled, Fried foodsEat a lot of processed foodsIf you have Metabolic Syndrome to any degree
27 Complimentary Market America AGE Support Products Arginine (Ultra Prime™)Isotonix OPC-3®NutriClean® Aloe/Ultimate Aloe™Curcumin ExtremeHeart Health™ Essential Omega IIIIsotonix® Vitamin D with K2
28 AGE control Summary Consume a Low AGE diet Help maintain healthy blood sugar levelsControl StressExercise regularlyNO SMOKINGTake Prime™ AGE Defense Formula regularly!
30 Ultra Prime™ Supports healthy levels of human growth hormone (HGH) Functions as a secretagogue to naturally increase the production and secretion of HGH by the pituitary glandRecreates a youthful, natural pattern of HGH production and release into the body.It is not HGHSafe and natural
31 Ultra Prime™Powerful combination of amino acids (the natural building blocks of proteins) that have been scientifically shown to effectively raise HGH levels.Taken with proper timing, exercise and a healthy diet you can turn back the clock and increase your HealthSpan!
32 Common Growth Hormone Inhibitors Stress hormones (Cortisol & Epinephrine)RelaxInsulinDon’t eat for 2 or more hours prior to bedtimeTime of daySleep well (hGH levels rise during sleep)
33 Ultra Prime™ -- Key Ingredients All of the major ingredients in the Prime secretagogues have published literature supporting their potential as nuitritional HGH secretagogues.BONUS!!!In addition, all of the major ingredients in these formulations have numerous other anti-aging related health benefits.
34 L-ArginineShown to be the amino acid that enhances Nitric Oxide (NO) production (Nobel Prize work in 1998) (not Nitrous oxide – laughing gas)Helps maintain healthy blood pressureHelp maintain erectile functionHelp maintain healthy blood flowEnhance Mood
35 Ultra Prime™ – UsageUse for hGH potentiation requires taking prior to bedtime on an empty stomachPost of a strenuous workout to enhance recoveryOther benefits can be realized taking it between meals
36 Ultra Prime™ Top of the line hGH secretagogues Extraordinary adjunct to support exerciseExcellent for nutritional support for CV healthGreat for nutritional support of basic immune function
37 Ultra Prime™ -- Summary Ultra Prime has so many more health benefits to offer you above and beyond hGH due to the unique, powerful and effective formulationTry it for yourself and see