2 Features of Aquagard-T Good Effervescent !Long Lasting !High Effectiveness !Very Convenient !Varied Application !
3 Aquagard-T… Aquagard-T is a effervescent tablet disinfectant. Aquagard-T is a very powerful disinfectant containing sodium dichloroisocyanurate (NaDCC) widely applied for the sterilization of drinking water, or fighting against infectious diseases, or act as disinfectant in raising livestock, poultry and fish.
4 Aquagard-T…Aquagard-T is an oxidising compound which releases chlorine to produce hypochlorous acid and hypochlorite ion in the presence of water.It is generally considered that the lethal action on organism is due to chlorination of cell protein or enzyme systems by nonionised hypochlorous acid, causing hydrolysis of peptidic chains of cellular membranes of pathogenic germs. Chlorine-releasing substances are bactericidal to most gram-positive and gram-negative bacteria, bacterial spores and viruses.
5 NaDCC (Sodium Dichloroisocyanurate) (Structural formula of NaDCC)
7 Aquagard-T : NaDCC (Sodium Dichloroisocyanurate) The germicidal activity of hypochlorous acid is 80 times higher than hypochlorite ion.The presence of HOCl in solution of chlorine containing compoundpH of NaOCl solutionspH of Aquagard-T solutions
8 Chlorine containing compound Chlorine used widely as a disinfectant and bleaching agentInorganic compound Sodium hypochlorite (NaOCl)Calcium hypochlorite (CaOCl)Chloline dioxide (ClO2)unstable, less germicidal activityOrganic compound Sodium dichloroisocyanurate (NaDCC)very stable, predominantly germicidal activity
9 Features of Aquagard-T Good effervescent high technique for making effervescent tabletsLong lasting free available chlorine is present for days in Aquagard-T solutionsHigh effectiveness broad spectrum disinfectant (active to spore forming bacteria, naked virus)Very convenient easy to handle and safeVaried application used widely for disinfection of poultry, pig, cattle and sheep, livestock houses and facilities, drinking water
10 Microbiocidal activity of various disinfectants Very SensitiveSensitiveResistantVery ResistantSeptic bacteria(Pasteurella sp)Enveloped virus(HC, TGE,ILT, IB, ND)Non-enveloped virus(Enterovirus,Adenovirus, FMD,IBD, Reo)Spore forming bacteria(B. anthracis,Clostridium)Weak Disinfectantssurfactant,quaternary ammonium chlorideIntermediate Disinfectantscresol, phenol,ortho, alcoholStrong Disinfectantschlorine, iodine,Aldehydes,ethylene oxide
11 Microbiocidal activity of Aquagard-T MicrobialsNaDCC* (ppm)Staphylococcus aureus1.12Escherichia coli0.83Salmonella typhiKlebsiella pneumoniae2.36Serratia marcescens1.14Yersinia enterocolitica0.72Pseudomonas aeruginosa2.00Saccharomyces cerevisiae72.0Candida albicans45.9* Total available chlorine
12 Bactericidal activity of Aquagard-T Phenol coefficiency of Aquagard-T against bacteriaTest strainsPhenol coefficiencyStaphylococcus aureus 209P28.5Salmonella pullorum 9-2525.5Erysipelothrix rhusiopathiae16.3Erysipelothrix rhusiopathiae fujisawa
13 Bactericidal activity of Aquagard-T Effectiveness of Aquagard-T against spore forming bacteriaDisinfectantsSporeBacillus subtilis ATCC9372Bacillus (natto) BN strainB. Cereus RIMDCl. Perfringens Type B NCTC3182Aspergillus oryzaeAquagard-T1:152(5)1:57(15)1:380(5)1:950(15)1:3,800(15)1:3,420(15)Iodine1:10(30)<1:10(30)1:10(15)<1:101:1,000(15)Benzalkonium chloride1:150(5)1:100(5)1:50(5)1:1,500(15)Amphotericsurfactant1:50(15)1:20(5)1:25(15)1:10(5)<1:50(15)Chlorhexidine1:200(5)1:300(15)1:100(15)1:1,200(15)Effective dilution rate, ( ) : Exposure time
14 Bactericidal activity of Aquagard-T The sporicidal activity of disinfectantsTest strainsNaDCCNaOClRemarksBacillus cereus17.21,060>62 timesBacillus subtilis30.91,510>49 times
15 Virucidal activity of Aquagard-T Virucidal activity against poultry virusesAdenovirusIBD virusILTvirusNDNaDCC○Iodine×Benzalkonium chloride○ : inactivated, × : not inactivated
16 Virucidal activity of Aquagard-T Virucidal activity against pig virusesFMDvirusAdenoJE virusTGEAujeszky’s disease virusRota virusHC virusNaDCC○Iodine×○ : inactivated, × : not inactivated
17 Fungicidal activity of Aquagard-T Test fungiMIC (mcg/ml) of Aquagard-TCandida albicans2.6Candida krusei26.3Aspergillus niger263.2Aspergillus fumigatusPenicillium citrinumTrichophyton verrucosumMicrosporum canisTrichophyton mentagrophytes
18 The efficacy test scope Total bacterial colony counts on foot bath in entrance of farmDisinfectantsChlorine contents or dilution rateElapsed days (day)135Aquagard-T418ppm-2.0×103NaOCl2.4×1051.7×105Quaternary ammonium chloride1:2007.0×1028.3×105Iodine1:2504.0×1017.0×103Orthodichlorobenzene8.7×103Control5.0×1042.0×1083.2×107Unit : CFU/ml, - : <1×101CFU/ml
19 Bactericidal activity Method : According to regulation of NVRQSExperiment : Research Institute for Veterinary Science in Konkuk Univ.Results :DiseaseConditionLight waterOrganic substanceSalmonella spp.1:7,2001:540Brucella spp.1:3,5001:400Streptococcus spp.1:8,0001:720It was tested by konkuk University according to the government regulation.As the result, lifeline is very strong bactericidal activity.Even in the(디) organic substance,The dilution rate is two hundred for salmonella.
20 Inclusion Hepatitis virus Virucidal activityMethod : According to regulation of NVRQSExperiment : Research Institute for Veterinary Science in Gyeongsang National Univ. and Cheonbuk National Univ.Results :DiseaseConditionLight waterOrganic substanceHog cholera virus1:12,0001:1,000PRRS virus1:12,5001:750New castle virus1:9,000Avian Influenza Virus1:15,0001:500Avian Pneumovirus1:7001:50Inclusion Hepatitis virus1:100It was tested by Seoul National Universityaccording to the government regulation.As the result, lifeline is very strong virucidal activity.Even in the organic substance,The dilution rate is two hundred for ND virus.And five hundred for avian influenza virus.
21 Composition of Aquagard-T Each tablet (13g) contains5g of Sodium dichloroisocyanurate(= 3g of available chlorine)andComponent A(effervescent agent)Component B(pH controlling agent)
22 Application of Aquagard-T Disinfection of virus and bacteria in livestock housing, farms (floor, wall), facilities and equipment, the animal bodyDrinking water treatmentTeat dip or spray (mastitis prevention)Disinfection of pathogenGeneral bacteria (Salmonella spp.), Brucella spp., Streptococcus spp. and so on.Foot and Mouth Disease virus, Hog Cholera virus, PRRS virus, Newcastle Disease virus, Avian Influenza Virus, Avian Pneumovirus, Inclusion Body Hepatitis virus and so on
23 Use of Aquagard-T (Bacteria) Recommended Dilution RateDisinfection TargetLowContamination GroupHighLivestock building, the surface of the animal's body, equipment, General automobilesThe Floor of the Livestock building, Manure,the body of the animal(dead or alive), Automobiles/VehiclesGeneral Bacteria(Salmonella spp.)1:7,200(1tablet per 93L of water)1:540(1tablet per 7L of water)Brucella spp.1:3,500(1tablet per 45L of water)1:400(1tablet per 5L of water)Streptococcusspp.1:8,000(1tablet per 104L of water)1:720(1tablet per 9.3L of water)* Dilution rate is the most effective dilution rate of results of determination of the efficacy of disinfectant against general bacteria and specific pathogen.
24 Use of Aquagard-T (Virus) Recommended Dilution RateDisinfection TargetLow Contamination GroupHigh Contamination GroupLivestock building, the surface of the animal's body, equipment, General automobilesThe Floor of the Livestock building, Manure, the body of the animal (dead or alive), Automobiles/VehiclesHog Cholera virus1:12,000(1 tablet per 156L of water)1:1,000(1 tablet per 13L of water)PRRS virus1:12,500(1 tablet per 163L of water)1:750(1 tablet per 9.7L of water)ND virus1:9,000(1 tablet per 117L of water)Avian Influenza Virus1:15,000(1 tablet per 195L of water)1:500(1 tablet per 6.5L of water)Avian Pneumovirus1:700(1 tablet per 9L of water)1:50(1 tablet per 650ml of water)Inclusion body hepatitis virus1:100(1 tablet per 1.3L of water)* Dilution rate is the most effective dilution rate of results of determination of the efficacy of disinfectant against general bacteria and specific pathogen.
25 Use of Aquagard-T (Water Treatment) Dissolve Aquagard-T in water tank every other day or every day if necessary.Dilute 1 tablet per 500 ~ 750 L of drinking water according to water quality and farm condition.
26 Use program for poultry Poultry houses and facilities- Thorough cleaning with water- Spray Aquagard-T solution not less than 2 timesbefore placement of chicks.- Spray Aquagard-T solution during growingperiod if necessary.
27 Use program for poultry Foot bath- For disinfect boots by dipping before entering each house, replace the Aquagard-T solutions every 5 days or sooner when soiled by heavy use.Transport- For prevention of disease transmission through trucks and crates by disinfecting them with Aquagard-T.- Use in wheel baths and renew every 5 days or according to volume of traffic.
28 Use program for dairy Dairy houses and facilities - Thorough cleaning with water- Spray Aquagard-T solution, eliminate all bacteria,viruses and fungi.
29 Use program for dairy to prevent Mastitis Preparation of disinfectionDissolve 1 Aquagard-T tablet per 1L of water and move to dipping cup or sprayer for disinfection.Prior to milking- Clean milk starts with clean teats.- Teat and udder spraying will remove all bacteria, viruses and fungi.After milking- Teat dip or spraying willdecontaminate the teats and preventmastitis
30 Use program for Milking Dipping methodSpray method1) Disinfection prior to milking- Removal of contaminant on teat2) Removal of disinfectant- With clean and disinfected towel3) Prior to milking- More than 5 times4) Massage and final cleaning- With clean and disinfected towel5) Attaching the milking mashing- Vacuum-blocking6) Disinfection after milking- Prevention of teat canal
35 Precautions of Aquagard-T Keep out of reach of children.Do not dissolve in strong alkali (over pH 10) or acidic (below pH 3) solution.Do not exceed the recommended dosage.For 5 days, from before 2 days to after 2 days of vaccination, do not disinfect drinking water.Do not place near fire or strong inflammables.Do not place in metallic vessel more than 2 hours.In case of drink diluted solution, immediately seek for medical advice.
36 SUNGIL PHARMA A concern of Thank YouSUNGIL PHARMAA concern of