1. Iron Deficiency and Anemia in CKD

2. Anemia in CKD

3. Clinical Gaps in Iron-Deficient Anemia

4. Why Treat Iron-Deficient Anemia in CKD?

5. Oral vs IV Iron

6. KDIGO Guidelines for Use of Iron Therapy

7. When to Use Iron Therapies

8. Definition of Anemia in CKD

9. Tests for Iron Deficiency in CKD

10. Commonly Used Tests

11. Hepcidin and HIF Regulation in Chronic Disease

12. There Are 2 Iron Deficiency Disorders

13. Iron and ESA therapy

14. IV FCM In Iron‐Deficient Patients With Chronic HF With And Without Anemia

15. IV Iron in Experimental Uremic Cardiomyopathy

16. Recommendations for Iron Therapy for Patients With CKD and Iron Deficiency

17. TREAT Study ESA in T2D and ND-CKD

18. Reduced ESA Use With IV Iron in Patients on Dialysis

19. Iron Infusion Leads to Reduced Platelets and Thrombotic Potential

20. KDIGO Anemia Management Recommendation

21. How to Use Iron Therapies

22. FIND-CKD

23. FIND-CKD: Results

24. FIND-CKD Cumulative Use of Alternative Anaemia Therapy

25. PIVOTAL Trial Design

26. PIVOTAL Cumulative Iron Dose

27. PIVOTAL Serum Ferritin Concentration

28. PIVOTAL Cumulative ESA Dose

29. PIVOTAL Death, MI, Stroke, or HF Hospitalization (Primary Endpoint)

30. PIVOTAL Cardiovascular Events

31. PIVOTAL Safety

32. Key Takeaways

33. Practical Strategies

34. ND-CKD Iron Deficiency

35. DD-CKD Iron Deficiency

36. Patient Case 1

37. Patient Case 2

38. Patient Case 2 (cont)

39. Abbreviations

40. Abbreviations (cont)

41. Abbreviations (cont)