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International normalized ratio self-management after mechanical heart valve replacement: is an early start advantageous?  Heinrich Körtke, MD, Reiner.

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Presentation on theme: "International normalized ratio self-management after mechanical heart valve replacement: is an early start advantageous?  Heinrich Körtke, MD, Reiner."— Presentation transcript:

1 International normalized ratio self-management after mechanical heart valve replacement: is an early start advantageous?  Heinrich Körtke, MD, Reiner Körfer, MD  The Annals of Thoracic Surgery  Volume 72, Issue 1, Pages (July 2001) DOI: /S (01)02656-X

2 Fig 1 Early mortality according to valve position and study group. (AVR = aortic valve replacement; MVR = mitral valve replacement.) The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

3 Fig 2 Late mortality according to valve position and study group. (Abbreviations as in Figure 1.) The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

4 Fig 3 Distribution of study drop-outs. ∗∗∗p ≤ 0.001.
The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

5 Fig 4 Reasons for study drop-outs.
The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

6 Fig 5 Distribution of risk factors between the two groups. 1 Men, body weight 15% higher than normal; women, body weight 10% higher than normal. 2 Blood pressure greater than 150/60 mm Hg. (AF = artrial fibrillation; n.s. = not significant.) ∗p ≤ 0.05. The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

7 Fig 6 ESCAT-1 observation period for 600 patients.
The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

8 Fig 7 Percentages within the therapeutic international normalized ratio (INR) range. (∗∗p ≤ 0.01; ∗∗∗p ≤ ) The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

9 Fig 8 Grade III complications, with a significant difference (∗p = 0.04) between the two groups. The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

10 Fig 9 Freedom from grade III thromboembolic or hemorrhagic complications. (post op = postoperative; cum. = cumulative.) The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)

11 Fig 10 Course of grade III complications during 24 months postoperatively. The Annals of Thoracic Surgery  , 44-48DOI: ( /S (01)02656-X)


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