1. Variants in CHEK2 Other than 1100delC Do Not Make a Major Contribution to Breast Cancer Susceptibility 
Mieke Schutte, Sheila Seal, Rita Barfoot, Hanne Meijers-Heijboer, Marijke Wasielewski, D. Gareth Evans, Diana Eccles, Carel Meijers, Frans Lohman, Jan Klijn, Ans van den Ouweland, P. Andrew Futreal, Katherine L. Nathanson, Barbara L. Weber, Douglas F. Easton, Michael R. Stratton, Nazneen Rahman 
The American Journal of Human Genetics 
Volume 72, Issue 4, Pages (April 2003)
DOI: /373965
Copyright © 2003 The American Society of Human Genetics Terms and Conditions

2. Figure 1
Abridged familial pedigrees with breast cancer who were positive for CHEK2 R117G. A, Pedigrees positive for R117G, as identified in the Variant Ascertainment Set. The index individual screened is indicated with an arrow. B, Pedigrees positive for R117G, as identified in the Variant Evaluation Set; all three individuals were screened as part of the analyses. Filled symbols indicate individuals with breast cancer. Hatched symbols indicate individuals with cancers other than breast cancer. bc = breast cancer; bbc = bilateral breast cancer; crc = colorectal cancer; lu ca = lung cancer; oe ca = esophageal cancer. The age at diagnosis is indicated after the tumor type.
The American Journal of Human Genetics  , DOI: ( /373965)
Copyright © 2003 The American Society of Human Genetics Terms and Conditions