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Emerging Targeted Therapies for NSCLC

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Presentation on theme: "Emerging Targeted Therapies for NSCLC"— Presentation transcript:

1 Emerging Targeted Therapies for NSCLC

2 Current Molecular Characterization

3 Overview of Approved Therapies

4 FLAURA: Final OS

5 Combining EGFR TKI and an Anti-Angiogenic

6 ASCEND-7: Ceritinib in Patients With CNS Disease

7 ALEX: Final PFS

8 Blood First Assay Screening Trial (BFAST)

9 Emerging RET Inhibitor: BLU-667

10 Emerging KRAS Inhibitor: AMG 510

11 Emerging MET Inhibitor: Tepotinib

12 Emerging HER2 Inhibitor: ZW25

13 Afatinib Activity in NRG1 Fusion-Positive NSCLC Cases

14 Updates to NTRK Inhibitor: Larotrectinib

15 Emerging NTRK/ROS1 Inhibitor: Repotrectinib

16 Updates to NTRK/ROS1 Inhibitor: Entrectinib

17 Clinical Impact of Emerging Targets and Treatments

18 Comments on the Cost of Molecular Testing

19 Key Takeaways

20 Looking Forward to 2020

21 Abbreviations

22 Abbreviations (cont)


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