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Topiramate-induced reactive granulomatous dermatitis
Sara Mater, BS, Jonathan J. Lee, MD, Jaroslaw Jedrych, MD, Misha Rosenbach, MD, Joseph C. English, MD JAAD Case Reports Volume 5, Issue 6, Pages (June 2019) DOI: /j.jdcr Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 1 Clinical findings at presentation. Pink papules coalescing into linear serpiginous cords and expansile annular plaques with central clearing. JAAD Case Reports 2019 5, DOI: ( /j.jdcr ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 2 Histologic findings (low power). Scanning magnification shows a palisaded and interstitial lymphohistiocytic infiltrate in the dermis. (Original magnification: ×5.) JAAD Case Reports 2019 5, DOI: ( /j.jdcr ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 3 Histologic findings (high power). Higher power highlights a palisade of histiocytes and multinucleated giant cells surrounding a focus of necrobiosis. (Original magnification: ×40.) JAAD Case Reports 2019 5, DOI: ( /j.jdcr ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions
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Fig 4 Clinical findings after discontinuation of topiramate. Four months after discontinuation of topiramate, the patient experienced near-complete resolution of dermatologic findings. JAAD Case Reports 2019 5, DOI: ( /j.jdcr ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions
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