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Schematic diagram of the DETECT study [56].
Schematic diagram of the DETECT study [56]. Inclusion criteria: systemic sclerosis or mixed connective tissue disease for ≥3 yrs; diffusing capacity of the lung for carbon monoxide <60% predicted; and no known pulmonary hypertension (PH) or left heart disease. Study commenced October 2008; cross-sectional data analysis 2011; longitudinal phase predicted completion end RHC: right heart catheterisation; ECG: electrocardiogram; Echo: echocardiography; NT-proBNP: N-terminal pro-brain natriuretic peptide; PAH: pulmonary arterial hypertension. C.P. Denton, and E. Hachulla Eur Respir Rev 2011;20: ©2011 by European Respiratory Society
![Schematic diagram of the DETECT study [56].](http://slideplayer.com/slide/17561987/103/images/1/Schematic+diagram+of+the+DETECT+study+%5B56%5D..jpg "Schematic diagram of the DETECT study [56]. Inclusion criteria: systemic sclerosis or mixed connective tissue disease for ≥3 yrs; diffusing capacity of the lung for carbon monoxide <60% predicted; and no known pulmonary hypertension (PH) or left heart disease. Study commenced October 2008; cross-sectional data analysis 2011; longitudinal phase predicted completion end RHC: right heart catheterisation; ECG: electrocardiogram; Echo: echocardiography; NT-proBNP: N-terminal pro-brain natriuretic peptide; PAH: pulmonary arterial hypertension. C.P. Denton, and E. Hachulla Eur Respir Rev 2011;20: ©2011 by European Respiratory Society.")
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