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New concepts for anticoagulant therapy in persons with hemophilia

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Presentation on theme: "New concepts for anticoagulant therapy in persons with hemophilia"— Presentation transcript:

1 New concepts for anticoagulant therapy in persons with hemophilia
by Roger E. G. Schutgens, Jeroen F. van der Heijden, Eveline P. Mauser-Bunschoten, and Pier M. Mannucci Blood Volume 128(20): November 17, 2016 ©2016 by American Society of Hematology

2 Recommendation for anticoagulant therapy in hemophilia patients with atrial fibrillation.
Recommendation for anticoagulant therapy in hemophilia patients with atrial fibrillation. Compared with our previous flowchart,2 notice the following adaptations: baseline FVIII/FIX changed from 30% to 20%; CHADS2 changed to CHA2DS2VASC; DOAC added; in patients with factor levels 1% to 20%, the threshold for the CHA2DS2VASC is raised to 4 and the option of catheter ablation is added. Roger E. G. Schutgens et al. Blood 2016;128: ©2016 by American Society of Hematology


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