1. Molecular surface models of the active-site cleft of OXA-66 (A) and OXA-40 (B), showing the absence of a hydrophobic bridge in OXA-66.
Molecular surface models of the active-site cleft of OXA-66 (A) and OXA-40 (B), showing the absence of a hydrophobic bridge in OXA-66. Using local numbering, the active-site serine 80 is shown in red. (A) Leucine 110 is in yellow, phenylalanine 111 is in blue, and tryptophan 222 is in pink; (B) tyrosine 112 is in blue, and methionine 223 is in pink.
Benjamin A. Evans, and Sebastian G. B. Amyes Clin. Microbiol. Rev. 2014; doi: /CMR