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Coronary artery bypass surgery as treatment for ischemic heart failure: the predictive value of viability assessment with quantitative positron emission.

Published byΕυθαλία Βονόρτας Modified over 4 years ago

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Presentation on theme: "Coronary artery bypass surgery as treatment for ischemic heart failure: the predictive value of viability assessment with quantitative positron emission."— Presentation transcript:

1 Coronary artery bypass surgery as treatment for ischemic heart failure: the predictive value of viability assessment with quantitative positron emission tomography for symptomatic and functional outcome  Domenico Pagano, FRCSa, Jonathan N. Townend, MDc, William A. Littler, MDc, Richard Horton, MBChBa, Paolo G. Camici, MD, FACCb, Robert S. Bonser, FRCSa  The Journal of Thoracic and Cardiovascular Surgery  Volume 115, Issue 4, Pages (April 1998) DOI: /S (98) Copyright © 1998 Mosby, Inc. Terms and Conditions

2 Fig. 1 Correlation between the number of viable dysfunctional LV segments and the absolute changes in LVEF (δ-EF). The equation for this relationship is Y = 1.2X + –3.97. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

3 Figure 2 Comparison of number of viable dysfunctional LV segments in patients with changes in LVEF (δ-EF) > 5 percentage points and those with ≤ 5 percentage points or deterioration. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

4 Figure 3 ROC curve demonstrating the sensitivity-specificity pairs for the number of PET-viable segments required to obtain improvements in LVEF greater than 5 percentage points after CABG. The arrow indicates the operator point associated with the best tradeoff between sensitivity (88%) and specificity (75%). The area fitted under the curve is 75% (trapezoid rule). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

5 Fig. 4 Exercise data for CHF–no-angina patients. Anaerobic threshold was achieved in all cases at baseline and at the follow-up study. The respiratory exchange ratio at peak exercise before CABG was 1.12 ± 0.07 and 1.1 ± 0.07 at follow-up. Heart rate at peak exercise was 129 ± 29 beats/min before CABG and 137 ± 18 beats/min at follow-up (p = 0.09). 95% CI = 95% confidence interval of the mean change. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /S (98) ) Copyright © 1998 Mosby, Inc. Terms and Conditions

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