Presentation is loading. Please wait.

Presentation is loading. Please wait.

Secular trends of bloodstream infections during neutropenia in 15 181 haematopoietic stem cell transplants: 13-year results from a European multicentre.

Published byInkeri Toivonen Modified over 4 years ago

Similar presentations

Presentation on theme: "Secular trends of bloodstream infections during neutropenia in 15 181 haematopoietic stem cell transplants: 13-year results from a European multicentre."— Presentation transcript:

1 Secular trends of bloodstream infections during neutropenia in 15 181 haematopoietic stem cell transplants: 13-year results from a European multicentre surveillance study (ONKO-KISS)  M. Weisser, C. Theilacker, S. Tschudin Sutter, R. Babikir, H. Bertz, T. Götting, M. Dettenkofer, W.V. Kern, A.F. Widmer  Clinical Microbiology and Infection  Volume 23, Issue 11, Pages (November 2017) DOI: /j.cmi Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

2 Fig. 1 Trends in incidence of bloodstream infections (BSI) during neutropenia after haematopoietic stem cell transplantation (HSCT). (A) Incidence of BSI in patients after autologous HSCT. (B) Incidence of BSI in patients after allogeneic HSCT. In patients after autologous HSCT, Gram-negative BSI increased (p 0.001), and Gram-positive BSI decreased significantly between 2002 and 2014 (p <0.001). In patients after allogeneic HSCT, Gram-negative BSI increased significantly (p <0.001). Trends in BSI incidence were examined by chi-square test for trend. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

3 Fig. 2 Trends in incidence of bloodstream infections (BSI) during neutropenia after haematopoietic stem cell transplantation (HSCT) according to pathogen. Incidence of BSI in patients after autologous HSCT (A) and in patients after allogeneic (HSCT) (B). Between 2002 and 2010, drop in incidence of BSI caused by coagulase-negative staphylococci was observed after autologous (p 0.028) and after allogeneic HSCT (p <0.001). Nonsignificant trends in incidence of BSI with coagulase-negative staphylococci occurred after In addition, incidence of BSI by Enterococcus spp. and Escherichia coli increased in patients with allogeneic HSCT (p <0.001, respectively). Trends in incidence of BSI were examined by chi-square test for trend. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

4 Fig. 3 Bloodstream infections in haematopoietic stem cell transplantation patients infected with multidrug-resistant bacteria. (A) Methicillin-resistant Staphylococcus aureus. (B) Vancomycin-resistant enterococci. (C) Extended-spectrum β-lactamase-producing Enterobacteriacea. n.c., not cultured. Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

5 Clinical Microbiology and Infection 2017 23, 854-859DOI: (10. 1016/j
Clinical Microbiology and Infection  , DOI: ( /j.cmi ) Copyright © 2017 European Society of Clinical Microbiology and Infectious Diseases Terms and Conditions

Download ppt "Secular trends of bloodstream infections during neutropenia in 15 181 haematopoietic stem cell transplants: 13-year results from a European multicentre."

Similar presentations

Gram-positive infections: lessons learnt and novel solutions

Gram-positive infections: lessons learnt and novel solutions
How to discriminate contamination from bloodstream infection due to coagulase- negative staphylococci: a prospective study with 654 patients  L. Elzi,

How to discriminate contamination from bloodstream infection due to coagulase- negative staphylococci: a prospective study with 654 patients  L. Elzi,
Bloodstream infections among carriers of carbapenem-resistant Klebsiella pneumoniae: etiology, incidence and predictors  S. Amit, H. Mishali, T. Kotlovsky,

Bloodstream infections among carriers of carbapenem-resistant Klebsiella pneumoniae: etiology, incidence and predictors  S. Amit, H. Mishali, T. Kotlovsky,
Women with symptoms of a urinary tract infection but a negative urine culture: PCR- based quantification of Escherichia coli suggests infection in most.

Women with symptoms of a urinary tract infection but a negative urine culture: PCR- based quantification of Escherichia coli suggests infection in most.
R. Cantón, A. Novais, A. Valverde, E. Machado, L. Peixe, F. Baquero, T

R. Cantón, A. Novais, A. Valverde, E. Machado, L. Peixe, F. Baquero, T
Clinical impact of a real-time PCR assay for rapid identification of Staphylococcus aureus and determination of methicillin resistance from positive blood.

Clinical impact of a real-time PCR assay for rapid identification of Staphylococcus aureus and determination of methicillin resistance from positive blood.
Incidence and outcome of Staphylococcus aureus endocarditis—a 10-year single-centre northern European experience  H. Asgeirsson, A. Thalme, M. Kristjansson,

Incidence and outcome of Staphylococcus aureus endocarditis—a 10-year single-centre northern European experience  H. Asgeirsson, A. Thalme, M. Kristjansson,
Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients 

Molecular characterization of methicillin-resistant Staphylococcus aureus isolated over a 2-year period in a Qatari hospital from multinational patients 
Time-trends for Gram-negative and multidrug-resistant Gram-positive bacteria associated with nosocomial infections in German intensive care units between.

Time-trends for Gram-negative and multidrug-resistant Gram-positive bacteria associated with nosocomial infections in German intensive care units between.
Control of multidrug-resistant Gram-negative bacteria in low- and middle-income countries—high impact interventions without much resources  N. Singh,

Control of multidrug-resistant Gram-negative bacteria in low- and middle-income countries—high impact interventions without much resources  N. Singh,
The efficacy and safety of daptomycin: first in a new class of antibiotics for Gram- positive bacteria  M.J. Rybak  Clinical Microbiology and Infection 

The efficacy and safety of daptomycin: first in a new class of antibiotics for Gram- positive bacteria  M.J. Rybak  Clinical Microbiology and Infection 
A. Simon, U. Bode, K. Beutel  Clinical Microbiology and Infection 

A. Simon, U. Bode, K. Beutel  Clinical Microbiology and Infection 
M. Kanaa, M.J. Wright, J.A.T. Sandoe 

M. Kanaa, M.J. Wright, J.A.T. Sandoe 
Clonal complex 398 methicillin-susceptible Staphylococcus aureus bloodstream infections are associated with high mortality  K. Bouiller, H. Gbaguidi-Haore,

Clonal complex 398 methicillin-susceptible Staphylococcus aureus bloodstream infections are associated with high mortality  K. Bouiller, H. Gbaguidi-Haore,
Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries  J.A. Otter, N.T. Mutters, E. Tacconelli, A.

Controversies in guidelines for the control of multidrug-resistant Gram-negative bacteria in EU countries  J.A. Otter, N.T. Mutters, E. Tacconelli, A.
Extended-spectrum β-lactamase/AmpC- and carbapenemase-producing Enterobacteriaceae in animals: a threat for humans?  J.-Y. Madec, M. Haenni, P. Nordmann,

Extended-spectrum β-lactamase/AmpC- and carbapenemase-producing Enterobacteriaceae in animals: a threat for humans?  J.-Y. Madec, M. Haenni, P. Nordmann,
Women with symptoms of a urinary tract infection but a negative urine culture: PCR- based quantification of Escherichia coli suggests infection in most.

Women with symptoms of a urinary tract infection but a negative urine culture: PCR- based quantification of Escherichia coli suggests infection in most.
Is the prevalence of antibiotic-resistant organisms changing in Canadian hospitals? Comparison of point-prevalence survey results in 2010 and 2012  V.

Is the prevalence of antibiotic-resistant organisms changing in Canadian hospitals? Comparison of point-prevalence survey results in 2010 and 2012  V.
Use of surveillance cultures and enteral vancomycin to control methicillin-resistant Staphylococcus aureus in a paediatric intensive care unit  K. Thorburn,

Use of surveillance cultures and enteral vancomycin to control methicillin-resistant Staphylococcus aureus in a paediatric intensive care unit  K. Thorburn,
Patients with refractory cytomegalovirus (CMV) infection following allogeneic haematopoietic stem cell transplantation are at high risk for CMV disease.

Patients with refractory cytomegalovirus (CMV) infection following allogeneic haematopoietic stem cell transplantation are at high risk for CMV disease.

Similar presentations

Ads by Google