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Transgenic mice with constitutively active NIK show increased tumor growth in bone. Transgenic mice with constitutively active NIK show increased tumor.

Published byClare Grant Modified over 4 years ago

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Presentation on theme: "Transgenic mice with constitutively active NIK show increased tumor growth in bone. Transgenic mice with constitutively active NIK show increased tumor."— Presentation transcript:

1 Transgenic mice with constitutively active NIK show increased tumor growth in bone.
Transgenic mice with constitutively active NIK show increased tumor growth in bone. A, 6-week-old NT3.catK and control (Ctl) littermates were injected with 1 × 104 B16-Fluc cells into left tibias, and right tibias were injected with PBS. Mice were imaged on days 5, 9, and 12 after tumor inoculation. Control, n = 12; NT3.catK, n = 8. B, representative images of A on day 12 are shown. C, tibias from A were scanned with μCT to measure BV/TV. D, representative μCT photos of C are shown. Data represent the mean ± SD; *, P < 0.05; **, P < 0.01. Chang Yang et al. Cancer Discovery 2013;3: ©2013 by American Association for Cancer Research

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