1. MHE diagnosis – Stroop test
Brain MRI findings in liver cirrhosis patients with subclinical hepatic encephalopathy Lupescu IC1, Iacob S2,4, Lupescu IG3,4, Gheorghe L2,4 1Neurology Department, Fundeni Clinical Institute, Bucharest, Romania 2Gastroenterology Department, Fundeni Clinical Institute, Bucharest, Romania 3Radiology and Medical Imaging Department, Fundeni Clinical Institute, Bucharest, Romania 4Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
BACKGROUND:
Liver cirrhosis
AIM: To correlate
MATERIAL AND METHODS:
RESULTS:
CONCLUSIONS:
Hepatic encephalopathy
Acquired hepato-cerebral degeneration
Hepatic myelopathy
Bilateral symmetric T1-hyperintensities of the globus pallidus and substantia nigra
Brain MRI findings
Presence of minimal hepatic encephalopathy (MHE)
Inclusion criteria
Liver cirrhosis
No overt HE
18-65 years-old
MHE diagnosis – Stroop test
≥ 145 seconds for patients <45 years-old
>190 seconds for patients ≥45 years-old
MRI – 1.5 Tesla
T1, T2, FLAIR, GRE, DWI, SWI, Spectroscopy
30 patients
Mean age = 50.2 ± 9.9 years-old
< 45 years-old: n=7
≥ 45 years-old: n=23
< 45 yo
≥ 45 yo p
MELD
16 ± 5
14 ± 5
0.3
Child
8 ± 2
0.6
No correlation was found between presence of brain MRI abnormalities and MHE diagnosis
Fischer exact test: p=0.12