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Oxytocin
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Methergine
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Hemabate
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Misoprostol
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Calcium gluconate
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30 units in 500 mL IV or 10 units IM
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0.2 mg (200 mcg) IM
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0.25 mg (250 mcg) IM or intramyometrial
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800 mcg rectally or 400-600 mcg orally
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1 ampule IVP or 2 ampules in 1 L IV fluid
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125-999 mL/hr Titrate to uterine tone.
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Every 2-4 hours. Up to 5 doses.
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Every mins. Up to 8 doses.
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No evidence to support giving more than 800 mcg rectally.
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Over 5 mins. Run wide open. Can safely repeat but benefit questionable.
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Potential fluid overload at total dose > 80 units
Potential fluid overload at total dose > 80 units. Do NOT administer IV push.
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Hypertension is contraindication
Hypertension is contraindication. Do not give IV due to sudden hypertension & CVA.
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Asthma is relative contraindication.
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Works most effectively when used with other medications.
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Assists with uterine contractility.
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