1. Connectivity in the basal ganglia.
Connectivity in the basal ganglia. While in PD the substantia nigra pars compacta (SNc) is preferentially affected, in PSP the major outputs to the thalamus (THAL), the substantia nigra pars reticulata (SNr) and globus pallidus internus (GPi) are also affected in addition to the subthalamic nucleus (STh) which is overactive in PD. Other abbreviations: cerebral cortex (CTX), striatum (STR), globus pallidus externus (Gpe). Courtesy of Dr Andrew Gillies, Institute for Adaptive & Neural Computation, Division of Informatics, University of Edinburgh, Edinburgh
Huw R Morris et al. Postgrad Med J 1999;75:
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