1. Breast cancer BRCA testing protocol
Patient with one or more of:
BC <30 years
Bilateral BC, both <50 years
Triple-negative BC, <50 years
BC + OC, any age
Other patients will qualify for genetic testing with a referral to clinical genetics, please see the referral criteria overleaf
Notes:
BC = Breast cancer, OC = Ovarian cancer
Actions by approved Cancer Team member:
Information sheet (MCG IS1) given to patient.
BRCA gene testing discussed.
Consent (MCG F1) obtained and filed in the notes.
Blood (2 EDTA sample taken at different times ) and request form (MCG F2) sent to lab.
More discussion required
Refer to Genetics
Cancer Team
Result sent to the requesting clinicians within 8 weeks
NO MUTATION
MUTATION
UNCLASSIFIED VARIANT
Actions by requesting clinician:
Result and information sheet (MCG IS2) sent to patient .
Referral made to clinical genetics only by request if required, please especially consider referring all patients < 30yrs or those with a complex family history
Actions by requesting clinician:
Appointment made to give the result to the patient
Result and information sheet (MCG IS3) given to patient.
Referral faxed to clinical genetics with consent form
Actions by requesting clinician:
Result and information sheet (MCG IS4) sent to patient.
Referral faxed to clinical genetics with consent form
MCG P1 v2
Reviewed: May 2019
Planned review: May 2021
Author: CJS
A clinical genetics appointment or telephone contact will be arranged for within 4 weeks of receiving the referral
A clinical genetics appointment or telephone contact will be arranged for within 12 weeks of receiving the referral
Genetics Team