Presentation is loading. Please wait.

Presentation is loading. Please wait.

Fig. 5 Adenosine A2BR agonist BAY attenuates bone loss in OVX animals.

Published byMarie-Paule Bernard Modified over 4 years ago

Similar presentations

Presentation on theme: "Fig. 5 Adenosine A2BR agonist BAY attenuates bone loss in OVX animals."— Presentation transcript:

1 Fig. 5 Adenosine A2BR agonist BAY 60-6583 attenuates bone loss in OVX animals.
Adenosine A2BR agonist BAY attenuates bone loss in OVX animals. (A to L) Administration of BAY and vehicle for 8 weeks in OVX animals (4 weeks after ovariectomy). Groups are compared to healthy control with no surgery and no treatment (CTL). (A) TRAP staining (purple). Scale bar, 50 μm. (B) Quantification of TRAP-positive cells on bone surface. n = 4. (C) Double-fluorescence bone labeling by calcein (green) and alizarin complexone (red). Scale bar, 100 μm. (D) Quantification of mineral apposition rate (MAR) from bone labeling images. (E) Quantification of bone formation rate (BFR/BS) from bone labeling images. n = 5. (F) Reconstructed microCT images of L4 vertebra. Scale bar, 500 μm. (G to J) Quantification of microCT images. (G) BMD. (H) BV/TV. (I) Tb.N. (J) Tb.Sp. n = 5. Mechanical measurement for (K) maximum load and (L) stiffness of tibia. n = 12. OV, ovariectomy, vehicle [dimethyl sulfoxide (DMSO)]; OB, ovariectomy, BAY (1 mg/kg). *P < 0.05, **P < 0.01, ***P < Yu-Ru V. Shih et al. Sci Adv 2019;5:eaax1387 Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

Download ppt "Fig. 5 Adenosine A2BR agonist BAY attenuates bone loss in OVX animals."

Similar presentations

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.

Fig. 3 The electrical contact of direct-printed and reconfigured liquid metals. The electrical contact of direct-printed and reconfigured liquid metals.
Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,

Fig. 2 Global production, use, and fate of polymer resins, synthetic fibers, and additives (1950 to 2015; in million metric tons). Global production, use,
Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)

Vibrational spectra of medieval human bones (Leopoli-Cencelle, Italy)
Fig. 1 Pump-probe signatures of vermilion (red HgS), black HgS, and metallic Hg. Pump-probe signatures of vermilion (red HgS), black HgS, and metallic.

Fig. 1 Pump-probe signatures of vermilion (red HgS), black HgS, and metallic Hg. Pump-probe signatures of vermilion (red HgS), black HgS, and metallic.
Fig. 3 Oil, gas, and FP water variations with time.

Fig. 3 Oil, gas, and FP water variations with time.
Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.

Fig. 5 Thermal conductivity of n-type ZrCoBi-based half-Heuslers.
Fig. 1 Map of water stress and shale plays.

Fig. 1 Map of water stress and shale plays.
Fig. 4 Super-resolution live imaging of calcium containing vesicle transports via lysosomes. Super-resolution live imaging of calcium containing vesicle.

Fig. 4 Super-resolution live imaging of calcium containing vesicle transports via lysosomes. Super-resolution live imaging of calcium containing vesicle.
Fig. 1 Examples of experimental stimuli and behavioral performance.

Fig. 1 Examples of experimental stimuli and behavioral performance.
Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.

Fig. 2 Some examples of weekly forecasts (the number of the forecasts are reported on Table 1). Some examples of weekly forecasts (the number of the forecasts.
Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.

Fig. 4 Resynthesized complex boronic acid derivatives based on different scaffolds on a millimole scale and corresponding yields. Resynthesized complex.
HT synthesis of boronic acids using the building block approach

HT synthesis of boronic acids using the building block approach
Fig. 6 Comparison of properties of water models.

Fig. 6 Comparison of properties of water models.
Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.

Fig. 1 Mean and median RCR (Relative Citation Ratio) of Roadmap Epigenomics Program research articles for each year. Mean and median RCR (Relative Citation.
Fig. 3 Scan rate effects on the layer edge current.

Fig. 3 Scan rate effects on the layer edge current.
Fig. 3 Rotation experiment, setup.

Fig. 3 Rotation experiment, setup.
Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.

Fig. 1 Product lifetime distributions for the eight industrial use sectors plotted as log-normal probability distribution functions (PDF). Product lifetime.
Fig. 1 Reference-fixing experiment, setup.

Fig. 1 Reference-fixing experiment, setup.
FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)

FTIR-ATR spectra of Neolithic faunal bones (Mora Cavorso cave, Italy)
Fig. 1 Concept of the livestock transition in China between 1980 and 2010. Concept of the livestock transition in China between 1980 and 2010. The left-

Fig. 1 Concept of the livestock transition in China between 1980 and Concept of the livestock transition in China between 1980 and The left-

Similar presentations

Ads by Google