1. Perspectives on Revised European Guidelines on Management of Bleeding and Coagulopathy Following Major Trauma

2. Faculty and Agenda

3. Key Highlights From the 2019 Guidelines on Management of Major Bleeding and Coagulopathy

4. Methodology of Guidelines' Development

5. Recommendation 15: Restrictive Volume Resuscitation Strategy

6. Recommendation 24: Initial Management of Massive Hemorrhage

7. Disseminating and Implementing the Guidelines

8. A Look Back at the 2016 Guidelines on Major Bleeding and Coagulopathy: What Was Working/What Was Not

9. The European Guideline on Management of Major Bleeding and Coagulopathy Following Trauma: Fifth Edition - Key Changes

10. Recommendation 32: Antithrombotic Agent Reversal

11. Recommendation 34: Direct Oral Anticoagulants - FXa Inhibitors

12. Recommendation 32: Rationale for Antithrombotic Agent Reversal

13. Recommendation 10: Coagulation Monitoring

14. Coagulopathy Diagnostic: Viscoelastic Techniques

15. Recommendation 28: Fibrinogen Supplementation

16. Promulgation and Implementation of the European Guidelines on Major Bleeding and Coagulopathy

17. FAST CT Scanning

18. Treatment Algorithms for Critical Trauma Cases

19. Role of Guidelines in Trauma Care

20. S3 Guideline on Treatment of Patients With Severe and Multiple Injuries

21. European Guidelines: Fifth Edition

22. Treatment Algorithm Pre-Hospital: Stop the Bleeding

23. The CRASH-2 Trial: Results of Administration of TXA

24. Fibrinogen and Hemostasis in Massive Bleeding

25. The Main Components of the Coagulation Cascade: Key Role of Fibrinogen

26. Fixed-Ratio Transfusion Protocol vs Goal-Directed Protocol

27. Treatment Algorithm: Block Lysis, Then Stimulate Clotting

28. Time Course of Plasma Fibrinogen During the First 7 Days After Trauma Categorized According to the Dose of FC Administered

29. Abbreviations

30. Abbreviations (cont)

31. Abbreviations (cont)