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Apicomplexan AMA1 in Host Cell Invasion: A Model at the Junction?

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Presentation on theme: "Apicomplexan AMA1 in Host Cell Invasion: A Model at the Junction?"— Presentation transcript:

1 Apicomplexan AMA1 in Host Cell Invasion: A Model at the Junction?
Christine R. Collins, Michael J. Blackman  Cell Host & Microbe  Volume 10, Issue 6, Pages (December 2011) DOI: /j.chom Copyright © 2011 Elsevier Inc. Terms and Conditions

2 Figure 1 Current Model of the Tight Junction
Schematic of the current model of the structure of the TJ (blue dot and inset) during erythrocyte invasion by the malaria merozoite, showing the proposed arrangement of the RON complex and its association with zoite-surface AMA1. The inset depicts the arrangement of the RON4/RON5 complex (blue) plus bound RON2 (green) which spans the host cell membrane to interact with parasite-surface AMA1 (brown). Cell Host & Microbe  , DOI: ( /j.chom ) Copyright © 2011 Elsevier Inc. Terms and Conditions

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