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The level of reactive oxygen species differentially regulates peroxiredoxin oxidation and mitogen-activated protein kinase signaling in human chondrocytes 

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Presentation on theme: "The level of reactive oxygen species differentially regulates peroxiredoxin oxidation and mitogen-activated protein kinase signaling in human chondrocytes "— Presentation transcript:

1 The level of reactive oxygen species differentially regulates peroxiredoxin oxidation and mitogen-activated protein kinase signaling in human chondrocytes  J.A. Collins, S.T. Wood, L. Poole, C. Furdui, R. Loeser  Osteoarthritis and Cartilage  Volume 24, Pages S179-S180 (April 2016) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1. Effect of menadione and FN-f on chondrocyte PRX oxidation
Figure 1. Effect of menadione and FN-f on chondrocyte PRX oxidation. Normal human articular chondrocytes were exposed to menadione (25 μM) or FN-f (1 μM) for 0–60 minutes and PRX oxidation was evaluated. Immunoblots shown are representative of three independent experiments. RM = reduced monomer; HM = hyperoxidized monomer. Data is presented as mean ± SEM of n = 3 independent experiments, *P = <0.05. Osteoarthritis and Cartilage  , S179-S180DOI: ( /j.joca ) Copyright © Terms and Conditions


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