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Quantitative expression of apoptosis-regulating genes in endometrium from women with and without endometriosis  Donald P. Braun, Ph.D., Jianchi Ding,

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Presentation on theme: "Quantitative expression of apoptosis-regulating genes in endometrium from women with and without endometriosis  Donald P. Braun, Ph.D., Jianchi Ding,"— Presentation transcript:

1 Quantitative expression of apoptosis-regulating genes in endometrium from women with and without endometriosis  Donald P. Braun, Ph.D., Jianchi Ding, Ph.D., Fehr Shaheen, M.D., James C. Willey, M.D., Nasir Rana, M.D., W. Paul Dmowski, M.D., Ph.D.  Fertility and Sterility  Volume 87, Issue 2, Pages (February 2007) DOI: /j.fertnstert Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

2 FIGURE 1 Quantitative TA measurement of the antiapoptotic and proapoptotic isoforms of the BCLX gene, designated BCLxL and BCLxS, respectively, in ECs from women with or without endometriosis. Data are plotted as the ratio of BCLxL:BCLxS for individual samples against the time of collection relative to the menstrual cycle. Braun. Apoptosis genes in endometrium. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

3 FIGURE 2 Quantitative TA measurement of the proapoptotic gene Caspase-1 in ECs from women with or without endometriosis. Individual values and times of collection relative to the menstrual cycle are shown for eutopic endometrium from women with (n = 10) or without (n = 6) endometriosis, and for ectopic endometrium from women with endometriosis (n = 6). Braun. Apoptosis genes in endometrium. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

4 FIGURE 3 Quantitative TA measurement of the proapoptotic gene p53 in ECs from women with or without endometriosis. Individual values and times of collection relative to the menstrual cycle are shown for eutopic endometrium from women with (n = 10) or without (n = 6) endometriosis, and for ectopic endometrium from women with endometriosis (n = 6). Braun. Apoptosis genes in endometrium. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

5 FIGURE 4 Quantitative TA measurement of the antiapoptotic gene DAD-1 in ECs from women with or without endometriosis. Individual values and times of collection relative to the menstrual cycle are shown for eutopic endometrium from women with (n = 10) or without (n = 6) endometriosis, and for ectopic endometrium from women with endometriosis (n = 6). Braun. Apoptosis genes in endometrium. Fertil Steril 2007. Fertility and Sterility  , DOI: ( /j.fertnstert ) Copyright © 2007 American Society for Reproductive Medicine Terms and Conditions

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