1. Added value and cascade effects of inflammatory marker tests in UK primary care: a cohort study from the Clinical Practice Research Datalink
by Jessica Watson, Chris Salisbury, Penny Whiting, Jonathan Banks, Yvette Pyne, and Willie Hamilton
BJGP
Volume 69(684):e470-e478
June 27, 2019
©2019 by British Journal of General Practice

2. Flowchart showing exclusions.
Flowchart showing exclusions. CPRD = clinical practice research datalink. CRP = C-reactive protein. ESR = erythrocyte sedimentation rate. PV = plasma viscosity.aMatched untested consists of subjects because, of the from the cohort who were randomly selected for matching, 72 had no suitable age, sex, and practice-matched control.
Jessica Watson et al. Br J Gen Pract 2019;69:e470-e478
©2019 by British Journal of General Practice

3. Test implications flowchart.
Test implications flowchart. Numbers and percentages do not add up to 100% due to rounding and because a small number of people developed more than one relevant disease outcome.
Jessica Watson et al. Br J Gen Pract 2019;69:e470-e478
©2019 by British Journal of General Practice

4. Incidence of relevant disease in relation to test result for CRP
Incidence of relevant disease in relation to test result for CRP. CRP = C-reactive protein.
Incidence of relevant disease in relation to test result for CRP. CRP = C-reactive protein.
Jessica Watson et al. Br J Gen Pract 2019;69:e470-e478
©2019 by British Journal of General Practice

5. Incidence of relevant disease in relation to test result for ESR
Incidence of relevant disease in relation to test result for ESR. ESR = erythrocyte sedimentation rate.
Incidence of relevant disease in relation to test result for ESR. ESR = erythrocyte sedimentation rate.
Jessica Watson et al. Br J Gen Pract 2019;69:e470-e478
©2019 by British Journal of General Practice

6. Incidence of relevant disease in relation to test result for PV
Incidence of relevant disease in relation to test result for PV. PV = plasma viscosity.
Incidence of relevant disease in relation to test result for PV. PV = plasma viscosity. For the small number (<0.5%) with one or more disease outcome; cancer superseded autoimmune disease, which superseded infections.
Jessica Watson et al. Br J Gen Pract 2019;69:e470-e478
©2019 by British Journal of General Practice