1. Model of the role of Vav proteins in apical maturation.
Model of the role of Vav proteins in apical maturation. (A,B) The crypt-surface epithelium from a WT and Vav1/2/3null mouse cecum is depicted. The cytoplasmic microtubule networks are depicted in green, actin networks in red and nuclei in blue. The lower and middle zones contain similar distributions and organization of actin and microtubules in WT and knockout mice. The upper zone enterocytes of the Vav1/2/3null mice are shorter and contain less-robust microtubule networks than the WT.
John Y. Liu et al. J Cell Sci 2009;122:
© The Company of Biologists Limited 2009