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Prospective Registration and Outcome-Reporting Bias in Randomized Controlled Trials of Eczema Treatments: A Systematic Review  Helen Nankervis, Akerke.

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Presentation on theme: "Prospective Registration and Outcome-Reporting Bias in Randomized Controlled Trials of Eczema Treatments: A Systematic Review  Helen Nankervis, Akerke."— Presentation transcript:

1 Prospective Registration and Outcome-Reporting Bias in Randomized Controlled Trials of Eczema Treatments: A Systematic Review  Helen Nankervis, Akerke Baibergenova, Hywel C. Williams, Kim S. Thomas  Journal of Investigative Dermatology  Volume 132, Issue 12, Pages (December 2012) DOI: /jid Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Flowchart of trial selection. GREAT, Global Resource of Eczema Trials; RCT, randomized controlled trial. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Proportion of eczema trials that were “registered” and “properly registered” among those published from January 2007 to July Total convenience sample=109 trials. Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions

4 Figure 3 Risk of bias among trials with and without registration (% at low, unclear, and high risk of bias). Journal of Investigative Dermatology  , DOI: ( /jid ) Copyright © 2012 The Society for Investigative Dermatology, Inc Terms and Conditions


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