1. Intra-University Pharmaceutical Technology & Education Workshop Dauch Alumni Center, Purdue University April 19th, 2006

2. Pharmaceutical Technology Design, development & manufacture of all components of drug products & pharmaceutical devices Active Pharmaceutical Ingredients –Organic molecules (small molecules) –Proteins & other biologics (large molecules) Scalable drug delivery platforms: oral, injectable, inhalable,transdermal Discovery API Process Development & Design Drug Form Development & Process Design Manufacturing Pharmaceutical Materials Science Clinical Trials Pharmaceutical Product Pipeline

3. Small Molecule API Process Produce Product Chemical Synthesis Dry Produc t Mill Product Isolate / Purify Product Crystallization Extraction Chromatography

4. Produce Product Large Molecule API Process Fermentation Cell Culture Physically Isolate Product Centrifugation Filtration Purify & Polish Product Isolate API in stable form Homogenization Chromatography Ultrafiltration Lyophilization Crystallization

5. Drug Delivery Platforms Solid Form Liquid Form Polymer Matrix

6. Solid Dosage Drug Product Manufacture API Crystallization Filtration / drying Oven Drying Fl. bed drying Blending Granulation Milling Compression Coating Lubrication Finished Tablet Compression

7. Intra-University Pharmaceutical Technology & Education Workshop April 19th, 2006, Dauch Alumni Center, Purdue University 8:00 a.m.Introduction and Opening Remarks Gintaras Reklaitis, Chemical Engineering Charles Rutledge, Vice President for Research 8:20 a.m. Overview of Pharmaceutical Technology & Education Stephen Byrn, Industrial and Physical Pharmacy 8:40 a.m. National Institute for Pharmaceutical Technology & Education Prabir Basu, Managing Director 9:00 a.m. NSF ERC on Structured Organic Composites Gintaras Reklaitis, Chemical Engineering 9:20 a.m. Institute for Advanced Pharmaceutical Technology, 21st Century R&T Venkat Venkatasubramanian, Chemical Engineering 9:40 a.m. Chao Center Craig Davis, Industrial and Physical Pharmacy 10:00 a.m. Break

8. Intra-University Pharmaceutical Technology & Education Workshop 10:20 a.m.NSF IUCRC for Pharmaceutical Processing Research Rodolfo Pinal, Industrial and Physical Pharmacy 10:40 a.m. Consortium for the Advanced Manufacturing of Pharmaceuticals / Particle Technology and Crystallization Consortia Stephen Byrn, Industrial and Physical Pharmacy 11:00 a.m. NIST Physical Properties Workshop Ken Morris, Industrial and Physical Pharmacy 11:20 a.m. Poster Session and Lunch

9. Intra-University Pharmaceutical Technology & Education Workshop 1:20 p.m. Controlled Drug Release Kinam Park, Industrial and Physical Pharmacy and Biomedical Engineering 1:40 p.m. Bioprocessing Michael Ladisch, Agricultural and Biological Engineering 2:00 p.m.Bioseparations Linda Wang, Chemical Engineering 2:20 p.m. Vaccine Technology Stanley Hem, Industrial and Physical Pharmacy 2:40 p.m. Product Pipeline Management Joseph Pekny, e-Enterprise Center & Chemical Engineering

10. Intra-University Pharmaceutical Technology & Education Workshop 3:00 p.m. MS Reg Compliance & CGMP Nancy Davis, Regulatory Education Program 3:20 p.m. MS in Pharmaceutical Engineering Carl Wassgren, Mechanical Engineering 3:40 p.m. Training in Bioprocessing Kari Clase, Industrial Technology 4:00 p.m. Panel Discussion: Future Directions for Pharmaceutical Technology and Education at Purdue 5:00 p.m. Adjournment