1. Continuity and Reproduction – Mitosis!

2. What happens in the life of a cell?
The Cell Cycle:
Interphase Mitosis (Cell Division) 2

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5. …what’s this? First: what is this structure? How does this structure
Why?
How does this structure
relate to biology? 5

6. Mitosis Notes! Cell division occurs in a series of stages, or PHASES .
These notes will be pasted into our journals!
Cell division occurs in a series of stages, or PHASES .
Chromosome: DNA strands that are tightly coiled
Chromatid: One of two identical copies of DNA that are held together by the centromere 6

7. CHROMOSOME
CENTROMERE
CHROMATID 7

8. 1st Phase: __INTERPHASE_______
Known as the “____IN BETWEEN______” stage
DNA is ___DUPLICATED__ (the # of DNA molecules double)
Cell __ORGANELLES__ also __DUPLICATE______ , in preparation for cell division.
DNA!
NUCLEUS! 8

9. 2nd Phase: _____PROPHASE______ Known as the “__PREPARATION___” stage
DNA __COILS__ to make __CHROMOSOMES__ .
Each chromosome is made of two sister _CHROMATIDS_ , connected at the __CENTROMERE____ .
The _NUCLEAR _MEMBRANE_ disappears, and the CENTRIOLES &_SPINDLE FIBERS are formed.
SPINDLE FIBERS!
NUCLEUS!
(Membrane
Disappears)
CENTRIOLES! 9

10. CHROMOSOME
CENTROMERE
CHROMATID 10

11. 3rd Phase: ____METAPHASE__ Known as the “__MIDDLE__” stage
The __CHROMATIDS___ line up in the ___MIDDLE__ of the cell.
The __SPINDLE___ fibers attach to the __CENTROMERE__ of each __CHROMOSOME__ .
SPINDLE FIBERS!
CENTRIOLES! 11

12. 4th Phase: _ANAPHASE_____ Known as the “___APART____” stage
The ____SPINDLE___ fibers pull the _SISTER_ ___CHROMATIDS____ apart to opposite ends of the cell . 12

13. 5th Phase: ___TELOPHASE______ Known as the “___TERMINATION__” stage
Two new __NUCLEI_____ form.
The DNA _____CHROMOSOMES___ will now ____UNCOIL___ .
NEW NUCLEUS
UNCOILED DNA 13

14. 6th Phase: ____CYTOKINESIS______ Known as the “___CUTTING___” stage
The __CYTOPLASM____ and _CELL_ __MEMBRANE____ pinch off to create two ___IDENTICAL___ cells! 14

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19. Practice with Mitosis “Mitosis is Atrocious” Worksheet
These worksheets will be collected! Work hard, and try your best! 19

20. Exit Quiz What are the phases of mitosis?
Which phase occurs when the chromosomes line up in the MIDDLE of the cell?
Which phase occurs when the chromosomes are pulled APART to opposite ends of the cell?