1. Selfish Stem Cells Compete with Each Other
Yukiko M. Yamashita 
Cell Stem Cell 
Volume 2, Issue 1, Pages 3-4 (January 2008)
DOI: /j.stem
Copyright © 2008 Elsevier Inc. Terms and Conditions

2. Figure 1 Models for Stem Cell Competition
(A) The bam/bgcn mutant GSCs (orange) “push” wild-type GSCs (green) out of the niche (blue) due to their higher expression of E-cadherin (red).
(B) The bam/bgcn mutant GSCs generate germline cell tumors, which result in a larger pool of GSCs/cystoblasts/cystocytes (pink) than that generated by wild-type GSCs (light green). As a result, they are more likely to give rise to GSCs via dedifferentiation during “natural turnover” of GSCs.
(C) GSCs with higher E-cadherin (red) levels may have a similar advantage during dedifferentiation.
Cell Stem Cell 2008 2, 3-4DOI: ( /j.stem )
Copyright © 2008 Elsevier Inc. Terms and Conditions