1. Lar function is not required for Stat92E accumulation in GSCs
Lar function is not required for Stat92E accumulation in GSCs. (A-B′) 0- to 1-day-old wild-type (A,A′) and Lar451/Lar2127 mutant (B,B′) adult Drosophila testes immunostained with anti-Stat92E (red, A,B; white, A′,B′) and anti-Vasa (green) antibodies.
Lar function is not required for Stat92E accumulation in GSCs. (A-B′) 0- to 1-day-old wild-type (A,A′) and Lar451/Lar2127 mutant (B,B′) adult Drosophila testes immunostained with anti-Stat92E (red, A,B; white, A′,B′) and anti-Vasa (green) antibodies. (A,B) GSCs (arrows) and CySCs (arrowheads) express Stat92E. (B′) A germ cell (long arrow) displaced from the hub expresses Stat92E. (C-D″) Expression of Stat92E (red, C,D; white, C′,D′) in homozygous Lar451 (arrows, C-C″) and Lar2127 (arrows, D-D″) mutant GSC clones 5 days PCI as compared with heterozygous control GSCs (arrowheads). Homozygous mutant GSCs (green outline in C″,D″) are detected by the absence of anti-GFP immunostaining (green, C,D; white C″,D″). The star indicates the Hub. Scale bars: 25 μm.
Shrividhya Srinivasan et al. Development 2012;139:
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