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Development and Application of a Risk Prediction Model for In-Hospital Stroke After Transcatheter Aortic Valve Replacement: A Report From The Society.

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Presentation on theme: "Development and Application of a Risk Prediction Model for In-Hospital Stroke After Transcatheter Aortic Valve Replacement: A Report From The Society."— Presentation transcript:

1 Development and Application of a Risk Prediction Model for In-Hospital Stroke After Transcatheter Aortic Valve Replacement: A Report From The Society of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy Registry  Vinod H. Thourani, MD, Sean M. O'Brien, PhD, John J. Kelly, MD, David J. Cohen, MD, MSc, Eric D. Peterson, MD, MPH, Michael J. Mack, MD, David M. Shahian, MD, Frederick L. Grover, MD, John D. Carroll, MD, J. Matthew Brennan, MD, MPH, Jessica Forcillo, MD, MSc, Suzanne V. Arnold, MD, Sreekanth Vemulapalli, MD, Susan Fitzgerald, RN, MS, David R. Holmes, MD, Joseph E. Bavaria, MD, Fred H. Edwards, MD  The Annals of Thoracic Surgery  Volume 107, Issue 4, Pages (April 2019) DOI: /j.athoracsur Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Calibration via 4-fold cross validation using 75% training and 25% testing samples. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 Comparison of observed versus expected in-hospital stroke rates. (AV = aortic valve; CI = confidence interval; EF = left ventricular ejection fraction; TIA = transient ischemic attack.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 Distribution of estimated site-specific odds ratios for in-hospital stroke. (IQR = interquartile range.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Site-specific odds ratios for in-hospital stroke with 95% Bayesian credible intervals. The 95% interval overlapped the null value (1.0; blue line) for 511 sites, was entirely above the null value for 10 sites, and was entirely below the null value for 0 sites. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

6 Supplemental Figure 1A The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

7 Supplemental Figure 1B The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

8 Supplemental Figure 1C The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

9 Supplemental Figure 1D The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2019 The Society of Thoracic Surgeons Terms and Conditions

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