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Endocardial hypothermia and pulmonary vein isolation with epicardial cryoablation in a porcine beating-heart model  Saqib Masroor, MD, MHS, Mary-Ellen.

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Presentation on theme: "Endocardial hypothermia and pulmonary vein isolation with epicardial cryoablation in a porcine beating-heart model  Saqib Masroor, MD, MHS, Mary-Ellen."— Presentation transcript:

1 Endocardial hypothermia and pulmonary vein isolation with epicardial cryoablation in a porcine beating-heart model  Saqib Masroor, MD, MHS, Mary-Ellen Jahnke, RN, Antoine Carlisle, DVM, Catherine Cartier, BSc, MEng, Jean-Pierre LaLonde, BSME, Timothy MacNeil, BS, Andre Tremblay, BSME, Fred Clubb, DVM, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 135, Issue 6, Pages e5 (June 2008) DOI: /j.jtcvs Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 A scatter plot depicting the lowest temperatures reached during epicardial cryoablation of right ventricular myocardium of varying thickness. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 A typical dose-response curve of right ventricular endocardial temperature during 5-minute epicardial cryoablation. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 A typical dose-response curve of left atrial endocardial temperature during 5-minute epicardial cryoablation. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 A cartoon depicting the possible position of the thermocouple in relation to the tip of the cryoprobe during epicardial cryoablation of the right ventricle (A) versus the left atrium (B; see text). PVI, pulmonary vein isolation. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

6 A, Surgifrost XL probe. B, Close-up view of the ablating segment with a fixed sheath covering the outer 270° circumference. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

7 Chromel-constantan thermocouple attached to a horizontally oriented steel wire, which prevents it from slipping out of the heart. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

8 Linear cryoablation over the right ventricle
Linear cryoablation over the right ventricle. Thermocouples are seen exiting under the cryoprobe. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

9 Epicardial cryoablation in progress with the Surgifrost XL probe tightened around all 4 pulmonary veins. The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions

10 Masson trichrome staining showing a transmural lesion.
The Journal of Thoracic and Cardiovascular Surgery  , e5DOI: ( /j.jtcvs ) Copyright © 2008 The American Association for Thoracic Surgery Terms and Conditions


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