1. Management of patients with obesity hypoventilation syndrome (OHS) from diagnosis to integrated care to modify health trajectories.
Management of patients with obesity hypoventilation syndrome (OHS) from diagnosis to integrated care to modify health trajectories. After being diagnosed with OHS, these patients are typically initiated on positive airway pressure (PAP) therapy (continuous positive airway pressure or noninvasive ventilation). Although respiratory insufficiency improves quite consistently in patients adherent to PAP therapy, pulmonary hypertension may also improve in some patients with OHS. There is no evidence that other cardiovascular and metabolic comorbidities improve with PAP treatment alone. Therefore, a multimodality therapeutic approach is necessary to combine PAP therapy with strategies aimed at weight reduction and increased physical activity. PaCO2: arterial carbon dioxide tension.
Juan F. Masa et al. Eur Respir Rev 2019;28:180097
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