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Biology of Blood and Marrow Transplantation

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Presentation on theme: "Biology of Blood and Marrow Transplantation"— Presentation transcript:

1 Biology of Blood and Marrow Transplantation
Enhancing the Functional Activity of Natural Killer Cells Against Myeloid Leukemia with the IL-15 Super-Agonist, ALT-803  Folashade Otegbeye, MBChB MPH, Nathan Mackowski, Evelyn Ojo, Stephen Moreton, Marcos de Lima, MD, David Wald, MD PhD  Biology of Blood and Marrow Transplantation  Volume 22, Issue 3, (March 2016) DOI: /j.bbmt Copyright © Terms and Conditions

2 Figure l ALT-8.3 enhances the activity and activating receptor expression pattern of ex vivo expanded NK cells as compared to IL-2. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions

3 Figure 2 ALT-803 injected mice exhibit enhanced afficacy of adoptively transferred NK cells in a mouse AML model system. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © Terms and Conditions


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