1. Significant association of FcɛRIα promoter polymorphisms with aspirin-intolerant chronic urticaria 
Jin-Sik Bae, MS, Seung-Hyun Kim, PhD, Young-Min Ye, MD, Ho Joo Yoon, MD, PhD, Chang-Hee Suh, MD, PhD, Dong-Ho Nahm, MD, PhD, Hae-Sim Park, MD, PhD 
Journal of Allergy and Clinical Immunology 
Volume 119, Issue 2, Pages (February 2007)
DOI: /j.jaci
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2. Fig 1
Effect of the −344C>T polymorphism on the transcription activity of the promoter on the FcɛRIα. A, Schematic representation of reporter gene constructs that contained the FcɛRIα promoter region with the −344 polymorphism. B, Relative luciferase production (ratio vs luciferase production by the promoter-less control vector, pGL3-Basic). The P value was determined by using the paired Student t test.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

3. Fig 2
Results of an EMSA for the −344C>T polymorphism using nuclear extracts obtained from RBL-2H3 cells. A, Nucleotide sequences of oligonucleotides used as probes and competitors. B, Differential binding of a nuclear protein to −344C/T alleles. C, Binding affinity of MAZ protein to −344C/T alleles. D, Identification of the transcription factor binding to −344 probe using competitive binding assay.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions

4. Fig 3
Comparison of histamine release from peripheral basophils obtained from AICU patients with the homozygous CC (N = 9) or heterozygous CT (N = 6) genotype of −344C>T. A, Stimulation with 3 μmol/L calcium ionophore A B, Stimulation with antihuman goat IgE antibodies. NS, Not significant.
Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci )
Copyright © 2007 American Academy of Allergy, Asthma & Immunology Terms and Conditions