1. Data Acquisition and Analysis for Sleep Architecture Study
Andrew Myers
Ross Fuller
Advisor: Dr. John Cohen
Special Thanks to Dr. Paul Harris

2. Objectives Sleep Study Data Acquisition Conversion of pH data
EEG, EMG, EOG, EKG, pH, Respiratory Rate, Oxygen Saturation
Conversion of pH data
Event recognition (pH < 4)
Data Analysis, Presentation
Graphical and Statistical analysis in MatLab

3. GERD is a common disorder...
40% of Americans suffer monthly.
7% of Americans suffer daily.
25% of Americans take an antacid >2x/month
It is the most common acid-related disorder.
It is becoming more common as the population ages.

4. What is not known?
The exact relationship between reflux events and sleep stage in normal volunteers and GERD patients.
How fundoplication affects objective sleep patterns in patients with GERD.

5. Fundoplication

6. The Sleep Study
The effects of fundoplication on subjects experiencing sleep disruption due to nocturnal gastroesophageal reflux disorder (GERD)
Conducted in a clinical setting at the Vanderbilt Medical Center’s General Clinical Research Center

7. Electrode and Probe Placement

8. Analysis Esophageal pH data downloaded
Sleep data interpreted by neurologist (blinded)
Questionnaire, pH, sleep data integrated on database