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B-cell epitopes as a screening instrument for persistent cow's milk allergy  Kirsi-Marjut Järvinen, MD, PhD, Kirsten Beyer, MD, Leticia Vila, MD, Pantipa.

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Presentation on theme: "B-cell epitopes as a screening instrument for persistent cow's milk allergy  Kirsi-Marjut Järvinen, MD, PhD, Kirsten Beyer, MD, Leticia Vila, MD, Pantipa."— Presentation transcript:

1 B-cell epitopes as a screening instrument for persistent cow's milk allergy 
Kirsi-Marjut Järvinen, MD, PhD, Kirsten Beyer, MD, Leticia Vila, MD, Pantipa Chatchatee, MD, Paula J. Busse, MD, Hugh A. Sampson, MD  Journal of Allergy and Clinical Immunology  Volume 110, Issue 2, Pages (August 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 An example of binding to decapeptides of cow's milk proteins of serum IgE antibodies by a patient with persistent CMA (upper rows) and a patient with transient CMA (lower rows) . Numbers indicate the residues corresponding to the peptide. α-lac, α-Lactalbumin; β-lac, β-lactoglobulin. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 Numbers of patients showing binding to each major IgE-binding epitope (represented as AA residues) of αs1-casein (A) , αs2-casein (B) , κ-casein (C) , and whey proteins (D) . Patients with persistent CMA are shown in filled bars , and those with transient CMA are shown in open bars . The total number of patients in each group is 10. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

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