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Michael F. Vaezi, MD, PhD, MSepi, Mohammed A

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1 Laryngeal Cancer and Gastroesophageal Reflux Disease: A Case-Control Study 
Michael F. Vaezi, MD, PhD, MSepi, Mohammed A. Qadeer, MD, Rocio Lopez, MS, MPH, Natalie Colabianchi, PhD  The American Journal of Medicine  Volume 119, Issue 9, Pages (September 2006) DOI: /j.amjmed Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Flowchart depicting the process of patient selection.
The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

3 Figure 2 Smoking duration and risk of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

4 Figure 3 Smoking intensity and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

5 Figure 4 Relationship between duration and intensity of smoking and laryngeal cancer development. OR=odds ratio; ppd=packs per day. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

6 Figure 5 Smoking cessation and the likelihood of developing laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

7 Figure 6 Alcohol intake (drinks per day) and risk of laryngeal cancer. LL=lower limit of 95% confidence interval; OR=odds ratio; UL=upper limit of 95% confidence interval. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions

8 Figure 7 Estimated probability of laryngeal cancer based on tobacco consumption and GERD status. GERD=gastroesophageal reflux disease. The American Journal of Medicine  , DOI: ( /j.amjmed ) Copyright © 2006 Elsevier Inc. Terms and Conditions


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