1. This month in Gastroenterology
Laura Harrell, Eugene B. Chang 
Gastroenterology 
Volume 128, Issue 1, Pages 1-3 (January 2005)
DOI: /j.gastro
Copyright © 2005 American Gastroenterological Association Terms and Conditions

2. Figure 1
Representative CTGF immunohistochemical staining. (A) Normal colon tissue (40× objective) and (B) colon polyp (100×). The left upper insert in (A) showed negative control IgG staining of colon adenocarcinoma. (C) High CTGF expression is found in differentiated adenocarcinoma tissue. CTGF is localized distinctly in the apical cytoplasm and membrane of the tumor cells. (D) Low CTGF protein expression is noted in a poor-differentiated adenocarcinoma specimen. (E) Analysis of survival (Kaplan-Meier) considering stage II and III colorectal cancer patients. Disease-free survival of 88 patients according to their tumor CTGF expression.
Gastroenterology  , 1-3DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

3. Figure 2
Prevalence of elevated alanine aminotransferase (ALT) activity by caffeine intake quintiles and coffee consumption categories (n = 5944). Error bars represent standard errors of percentages. *Indicated P < .05 compared to lowest quintile for caffeine or 0 cups/day for coffee.
Gastroenterology  , 1-3DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

4. Figure 3
Confocal immunofluorescence microscopy images showing actinin-4 expressed at the leading edge and the actin cytoskeleton in DLD1 Tet-off ACTN4 cell clusters. Actinin-4 protein was detected using anti-HA antibody (green) and filamentous actin polymers were detected by phalloidin (red). Panel A is a magnified area of B. (C) Laparotomy findings in a SCID mouse that had received an injection of DLD1 Tet-off ACTN4 cells (expressing α-actinin) into its spleen 5 weeks earlier. Arrows indicate metastatic nodules.
Gastroenterology  , 1-3DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions

5. Figure 4
Effect of survivin suppression on RGM-1 cell integrity and indomethacin induced cell injury. (A) Western blots showing survivin expression in mock (no oligo), 200 nmol/L of nonspecific RNA (control), or 200 nmol/L survivin siRNA (siRNA) transfected cells. β-actin served as control for protein loading. (B) Quantification of survivin expression in transfected cells. (C) Percent cell injury (LDH release) in response to the indicated transfections + indomethacin treatment. Cell injury was normalized to the positive control (sonicated cells). (B and C) Cell injury was compared with that from mock transfection, *P < .05 (n = 9).
Gastroenterology  , 1-3DOI: ( /j.gastro )
Copyright © 2005 American Gastroenterological Association Terms and Conditions