1. Histochemical assessment of nitric oxide synthase activity in aortic endothelial cells of streptozotocin-induced diabetic rats 
M Shafiei, M Nobakht, M Fattahi, L Kohneh-Shahri, M Mahmoudian 
Pathophysiology 
Volume 10, Issue 1, Pages (December 2003)
DOI: /j.pathophys

2. Fig. 1
Concentration-dependent relaxation to the endothelium-dependent vasodilator acetylcholine in control (n=8) and diabetic (n=8) aortic rings precontracted with submaximal concentrations of phenylephrine. Values are expressed as the mean±S.E.M. (*P<0.01).
Pathophysiology  , 63-67DOI: ( /j.pathophys )

3. Fig. 2
Concentration-dependent relaxation to isosorbide dinitrate in control and diabetic aortic rings with endothelium ((a), n=8) or without endothelium ((b), n=8) precontracted with submaximal concentrations of phenylephrine. Values are expressed as the mean±S.E.M.
Pathophysiology  , 63-67DOI: ( /j.pathophys )

4. Fig. 3
Light micrograph of aorta obtained from healthy rat. No staining could be detected in control sections after omitting βNADP in NADPH-diaphorase staining.
Pathophysiology  , 63-67DOI: ( /j.pathophys )

5. Fig. 4
Light micrograph of aorta obtained from healthy rat. NADPH-diaphorase histochemistry reveals eNOS activity in endothelial cells that strongly are stained.
Pathophysiology  , 63-67DOI: ( /j.pathophys )

6. Fig. 5
Light micrograph of aorta obtained from diabetic rat. Endothelial cells show much less staining for NADPH-diaphorase. Arrows point to the sites of disruption in endothelial cell membranes.
Pathophysiology  , 63-67DOI: ( /j.pathophys )