1. European Urology Oncology
Development and Validation of a Lookup Table for the Prediction of Metastatic Prostate Cancer According to Prostatic-specific Antigen Value, Clinical Tumor Stage, and Gleason Grade Groups 
Felix Preisser, Marco Bandini, Sebastiano Nazzani, Elio Mazzone, Michele Marchioni, Zhe Tian, Felix K.H. Chun, Fred Saad, Alberto Briganti, Alexander Haese, Francesco Montorsi, Hartwig Huland, Markus Graefen, Derya Tilki, Pierre I. Karakiewicz 
European Urology Oncology 
DOI: /j.euo
Copyright © 2019 European Association of Urology Terms and Conditions

2. Fig. 1
Loess plots depicting metastatic prostate cancer rates plotted on a logarithmic scale against the logarithmic prostatic-specific antigen value, stratified by clinical tumor stages, in the entire (A) SEER cohort and (B–F) biopsy Gleason grade subgroups. The red horizontal line represents 1%. GGG=Gleason grade group; mPCa=metastatic prostate cancer; PSA=prostatic-specific antigen; SEER=Surveillance, Epidemiology, and End Results.
European Urology Oncology DOI: ( /j.euo )
Copyright © 2019 European Association of Urology Terms and Conditions

3. Fig. 2
Calibration plot of the lookup table within the validation cohort. ROC=receiver operating characteristic.
European Urology Oncology DOI: ( /j.euo )
Copyright © 2019 European Association of Urology Terms and Conditions

4. Fig. 3
Decision curve analysis for the lookup table. Net benefit of a strategy involving treating all patients (grey line) or no patients (black line), or according to the lookup table predictions (dotted line).
European Urology Oncology DOI: ( /j.euo )
Copyright © 2019 European Association of Urology Terms and Conditions