1. Skeletal muscle ventricle pressure-volume properties conform to dynamic and static conditioning 
Kenneth J Gustafson, PhD, James D Sweeney, PhD, John Gibney, MD, Lee Ann Fiebig-Mathine, PhD 
The Annals of Thoracic Surgery 
Volume 76, Issue 3, Pages (September 2003)
DOI: /S (03)

2. Fig 1
Skeletal muscle ventricle (SMV) implant system. The SMV implants had a rigid longitudinal axis and expanded radially (dashed line). Dynamic SMVs were connected to an external pneumatic compliance chamber to allow dynamic shortening. An access port was used for pressure monitoring and daily testing sessions.
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

3. Fig 2
Resting pressure progression for a high pressure skeletal muscle ventricle (SMV). The SMV resting pressure was increased after the SMV had adapted to the previous increase in pressure. The end pressure is the pressure that the SMV was set to at the end of the daily testing session. The open pressure is the initial SMV resting pressure at the time of testing, typically 24 hours later. Pneumatic (high pressure and low pressure) SMV pressures varied and decreased 36% ± 9.0% daily owing to pneumatic system air loss, temperature variations, and SMV volume expansion. Squares = end pressure; circles = open pressure. (PO = postoperative.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

4. Fig 3
The progression of passive pressure-volume curves for selected testing sessions are shown for representative skeletal muscle ventricles (SMVs) from each group. The passive pressure-volume properties shifted corresponding to the stable, increasing, and decreasing SMV volume in isovolumetric (Iso Vol) (top), high pressure (HiP) (middle), and low pressure (LowP) (bottom) SMVs, respectively (arraows). Postoperative dates: (top) circles = 13, squares = 18, diamonds = 28, Xs = 37, vertical dashes = 46, triangles = 56; (Middle) circles = 21, squares = 28, diamonds = 42, Xx = 49, vertical dashes = 55, triangles = 63; (bottom) circles = 15, squares = 21, diamonds = 33, Xx = 56.
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

5. Fig 4
The progression of active pressure-volume curves for selected testing sessions are shown for representative skeletal muscle ventricles (SMVs) from each group. Pressures were evoked with single stimuli (twitches). The volume for peak pressure generation shifted toward the stable, increasing, and decreasing SMV volume in isovolumetric (IsoVol) (top), high pressure (HiP) (middle), and low pressure (LowP) (bottom) SMVs, respectively (arrows). Postoperative dates: (top) circles = 14, squares = 29, diamonds = 49, Xs = 56; (middle) circles = 18, squares = 42, diamonds = 52, Xs = 63; (bottom) circles = 15, squares = 21, diamonds = 33.
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

6. Fig 5
Progressions of the peak evoked (twitch) isovolumetric pressures generated during testing sessions for skeletal muscle ventricles (SMVs) in each group. Evoked pressures before postoperative (PO) date 21 are underestimated. (IsoVol = isovolumetric; HiP = high pressure; LowP = low pressure.)
The Annals of Thoracic Surgery  , DOI: ( /S (03) )

7. Fig 6
The volume expansion of each high pressure (HiP) skeletal muscle ventricle (SMV) is shown as a function of postoperative (PO) date. The SMV volumes at a pressure of 40 mm Hg are shown. Every HiP SMV expanded in volume during conditioning and did not exhibit a decrease in the rate of SMV volume expansion. A linear regression line based on the pooled data from all experiments is shown. The average rate of expansion was 0.50 ± mL per day over the conditioning period.
The Annals of Thoracic Surgery  , DOI: ( /S (03) )