1. Status of the executioner step of apoptosis in human with normal spermatogenesis and azoospermia 
Aline Bozec, Ph.D., Souheila Amara, Ph.D., Basma Guarmit, M.Sc., Jacqueline Selva, M.D., Ph.D., Martine Albert, M.D., Jacques Rollet, M.D., Mohamed El Sirkasi, Ph.D., Francois Vialard, Pharm.D., Ph.D., Marc Bailly, M.D., Mohamed Benahmed, M.D., Ph.D., Claire Mauduit, Pharm.D., Ph.D. 
Fertility and Sterility 
Volume 90, Issue 5, Pages (November 2008)
DOI: /j.fertnstert
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Identification of caspases, XIAP, and Smac/DIABLO in human testes. The expression of effector caspase-3, -6, and -7, of initiator caspase-8 and -9, and of XIAP and Smac/Diablo was evaluated (A) by reverse transcriptase-polymerase chain reaction (RT-PCR) and (B) by Western blotting on human testicular tissue with normal histology.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

3. Figure 2
Immunolocalization of caspases, XIAP, and Smac/DIABLO in human testes. The immunolocalization of the different proteins was evaluated in human testes with normal histology for (A) caspase-3, (B) caspase-6, (C) XIAP, (D) Smac/DIABLO, (E) caspase-8, (F) caspase-9. In nonobstructive azoospermia, active caspase-3 was localized in spermatogenetic arrest at pachytene spermatocyte (G) or spermatid (H) level. L = Leydig cells; S = Sertoli cells; black arrow = peritubular myoid cells; go = spermatogonia; cy = spermatocytes; ti = spermatids. Bar = 50 μm, inset bar = 200 μm. AEC (A, B, G, and H) or DAB (C, D, E, and F) staining was used.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions

4. Figure 3
Evaluation of apoptosis in azoospermia. The TUNEL approach was used to evaluate apoptosis in testicular biopsies originating from (A) congenital agenesis of vas deferens (CAVD); (B) testicular inflammation (IN); (C) hypospermatogenesis (HYPO), and (D) spermatogenetic arrest (SA). (E) The number of TUNEL-positive cells was determined per surface unit (13,225 μm2) in each patient group. Each patient is represented by a dot and the mean is represented by a bold line. See text for abbreviations.
Fertility and Sterility  , DOI: ( /j.fertnstert )
Copyright © 2008 American Society for Reproductive Medicine Terms and Conditions