1. MATRIX: Radial vs. Femoral
Trial design: Subjects with acute coronary syndromes were randomized to radial access (n = 4,197) vs. femoral access (n = 4,207).
Results
(p = 0.031)
Death, MI, or stroke: 8.8% of the radial group vs. 10.3% of the femoral group (p = 0.031; this exceeded the prespecified α level of 2.5%)
Death, MI, stroke, or BARC (type 3 or 5) major bleeding: 9.8% vs. 11.7% (p = ), respectively, for radial vs. femoral
10.3 %
8.8
Conclusions
Among patients with acute coronary syndromes, radial access was not associated with a reduction in major adverse cardiovascular events
However, radial access was associated with a reduction in net adverse events, including major bleeding
Radial access
Femoral access
Valgimigli M, et al. Lancet 2015;Mar 13:[Epub]