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Treosulfan, Fludarabine, and 2-Gy Total Body Irradiation Followed by Allogeneic Hematopoietic Cell Transplantation in Patients with Myelodysplastic Syndrome.

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Presentation on theme: "Treosulfan, Fludarabine, and 2-Gy Total Body Irradiation Followed by Allogeneic Hematopoietic Cell Transplantation in Patients with Myelodysplastic Syndrome."— Presentation transcript:

1 Treosulfan, Fludarabine, and 2-Gy Total Body Irradiation Followed by Allogeneic Hematopoietic Cell Transplantation in Patients with Myelodysplastic Syndrome and Acute Myeloid Leukemia  Boglarka Gyurkocza, Jonathan Gutman, Eneida R. Nemecek, Merav Bar, Filippo Milano, Aravind Ramakrishnan, Bart Scott, Min Fang, Brent Wood, John M. Pagel, Joachim Baumgart, Colleen Delaney, Richard T. Maziarz, Brenda M. Sandmaier, Elihu H. Estey, Frederick R. Appelbaum, Barry E. Storer, Hans Joachim Deeg  Biology of Blood and Marrow Transplantation  Volume 20, Issue 4, Pages (April 2014) DOI: /j.bbmt Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

2 Figure 1 Cumulative incidence of GVHD: (A) acute, grades II-IV and III-IV, and (B) chronic, extensive. Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

3 Figure 2 OS, relapse mortality, and NRM (N = 96).
Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

4 Figure 3 Cytogenetics and outcome for (A and B) all patients, (C and D) patients with MDS (n = 36), and (E and F) patients with AML (n = 60). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions

5 Figure 4 Pretransplant MRD and relapse (A) and survival (B) in patients with AML in morphologic remission (n = 56). Biology of Blood and Marrow Transplantation  , DOI: ( /j.bbmt ) Copyright © 2014 American Society for Blood and Marrow Transplantation Terms and Conditions


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