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Qualia Current Biology Volume 22, Issue 10, Pages R392-R396 (May 2012)

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Presentation on theme: "Qualia Current Biology Volume 22, Issue 10, Pages R392-R396 (May 2012)"— Presentation transcript:

1 Qualia Current Biology Volume 22, Issue 10, Pages R392-R396 (May 2012)
Ryota Kanai, Naotsugu Tsuchiya  Current Biology  Volume 22, Issue 10, Pages R392-R396 (May 2012) DOI: /j.cub Copyright © 2012 Elsevier Ltd Terms and Conditions

2 Figure 1 Qualia in broad sense and narrow sense.
(A) The broad sense definition regards the entire phenomenal experience at one moment, including vision, audition, olfaction and so on, as one quale. Note that within each modality there are submodes such as colour and shape for vision. The narrow sense definition takes such submodes as qualia. (Adapted with permission from Balduzzi and Tononi 2009.) (B) Comparison of the broad and narrow definitions. In the broad sense definition, the quale for the colour of a red disk presented in the left visual hemisphere is considered distinct from the quale for the same stimulus shown in the right visual field, because the experience as a whole differs between the two situations. In the narrow sense definition, qualia for colour at different locations can be meaningfully compared. Current Biology  , R392-R396DOI: ( /j.cub ) Copyright © 2012 Elsevier Ltd Terms and Conditions

3 Figure 2 Neural correlates of consciousness (NCC), access (NCA) and qualia (NCQ). (A) Wilke and colleagues used a generalized flash suppression paradigm (Wilke et al. 2009) to manipulate the visibility of a red circular stimulus invisible or visible by stimulus configuration. The neuronal activity is compared with the control condition where the stimulus was invisible due to its physical removal. (B,C) While recording spiking activity in the pulvinar, some neurons signalled the visibility of the stimulus independent of the presence (B) or absence (C) of report, suggesting that these spiking activities are a possible NCQ. Solid lines indicate the difference in firing rate between visible vs. (perceptually) invisible. Dotted lines indicate the difference in firing rate between visible versus physical removal trials. (D,E) The alpha (9–14 Hz) and beta (15–30 Hz) band power of the local field potential in the pulvinar distinguished the visibility only when the monkey reported the visibility (D) but not when they did not report the visibility of the stimulus (E), indicating that these are likely to be NCA, but not NCQ. (Modified with permission from Wilke et al ) Current Biology  , R392-R396DOI: ( /j.cub ) Copyright © 2012 Elsevier Ltd Terms and Conditions

4 Figure 3 Rewiring experiments in ferrets.
(A) The intact visual cortex in the right hemisphere, serving as a control, receives input from the left visual field on the retina via the lateral geniculate nucleus (LGN) and lateral posterior nucleus (LP) as well as superior colliculus (SC). The intact auditory cortex receives inputs from the ear via the inferior colliculus (IC) and the medial geniculate nucleus (MGN) of the thalamus. The rewired left hemisphere, whose SC and connection from the inferior colliculus (IC) to MGN are destroyed, receives visual inputs at the visual cortex via LGN and LP and at the auditory cortex via the rewired retina-MGN pathway. Later, the LGN/LP pathway was lesioned to isolate the MGN pathway. (B) The rewired ferrets were trained to discriminate the light impinging on the intact left visual field and sound from the speaker. After successful training with the intact visual field, the ferrets responded to the light stimulation to the rewired visual field (projecting to the auditory cortex) as if it were a visual stimulus. (C) Long-range horizontal connection pattern in V1, normal A1 and rewired A1. The panels show the distribution of connected neurons revealed by retrograde labelling by cholera toxin B whose injection site is marked by the star symbols. Panels A and B adapted with permission from von Melchner et al. (2000); panel C adapted with permission from Sharma et al. (2000). Current Biology  , R392-R396DOI: ( /j.cub ) Copyright © 2012 Elsevier Ltd Terms and Conditions


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