1. Beware of Underlying Malignancy: Acquired Ichthyosis
Andrew P. Word, MD, Rachael Cayce, MD, Amit G. Pandya, MD 
The American Journal of Medicine 
Volume 127, Issue 3, Pages (March 2014)
DOI: /j.amjmed
Copyright © 2014 Elsevier Inc. Terms and Conditions

2. Figure 1
Acquired ichthyosis was marked by diffuse large plate-like scale with underlying pink erythema on the patient's lower extremity.
The American Journal of Medicine  , DOI: ( /j.amjmed )
Copyright © 2014 Elsevier Inc. Terms and Conditions

3. Figure 2
A 4-cm right axillary lymph node proved to be evidence of nodal anaplastic large cell lymphoma.
The American Journal of Medicine  , DOI: ( /j.amjmed )
Copyright © 2014 Elsevier Inc. Terms and Conditions

4. Figure 3
Histopathologic examination of a skin biopsy revealed acanthosis with laminated hyperkeratosis and a thin granular layer (hematoxylin and eosin, 100x).
The American Journal of Medicine  , DOI: ( /j.amjmed )
Copyright © 2014 Elsevier Inc. Terms and Conditions

5. Figure 4
After 2 cycles of chemotherapy, the patient had normal-appearing skin at a site on the lower extremity where he previously had plate-like scale. In addition, repeat positron emission tomography indicated resolution of lymphadenopathy.
The American Journal of Medicine  , DOI: ( /j.amjmed )
Copyright © 2014 Elsevier Inc. Terms and Conditions