Presentation is loading. Please wait.

Presentation is loading. Please wait.

Schematic representation of experimental design for BSp dietary treatments. Schematic representation of experimental design for BSp dietary treatments.

Published byChloe Jennifer Harris Modified over 4 years ago

Similar presentations

Presentation on theme: "Schematic representation of experimental design for BSp dietary treatments. Schematic representation of experimental design for BSp dietary treatments."— Presentation transcript:

1 Schematic representation of experimental design for BSp dietary treatments.
Schematic representation of experimental design for BSp dietary treatments. The upper bar represents different life stages in the mother and female offspring. Transgenic mice were administered the BSp diet under different exposure time points: (i) Control: mice were fed ad libitum (AL) with the control AIN-93G diet; (ii) prenatal/maternal BSp treatment (Pre-BSp): The BSp diet was given to the mother from conception (12 weeks) until weaning (PD28); (iii) postnatal early-life BSp treatment (Early-BSp): The BSp diet from postnatal 4 weeks of age until termination of the experiment; (iv) postnatal adult BSp treatment (Adult-BSp): The BSp diet from postnatal 8 weeks of age until termination of the experiment. Mice were mated at 12 weeks of age following 3 weeks of gestation. Pups were weaned at 4 weeks of age (PD28). In the prenatal/maternal BSp group, weaned female offspring were maintained on the control diet throughout their lifespan until termination of the experiment and monitored for tumor growth weekly. For postnatal treatments, female mice were born to mothers administered the control AIN-93G diet and monitored for tumor growth weekly after weaning. Yuanyuan Li et al. Cancer Prev Res 2018;11: ©2018 by American Association for Cancer Research

Download ppt "Schematic representation of experimental design for BSp dietary treatments. Schematic representation of experimental design for BSp dietary treatments."

Similar presentations

I.1 ii.2 iii.3 iv.4 1+1=. i.1 ii.2 iii.3 iv.4 1+1=

I.1 ii.2 iii.3 iv.4 1+1=. i.1 ii.2 iii.3 iv.4 1+1=
I.1 ii.2 iii.3 iv.4 1+1=. i.1 ii.2 iii.3 iv.4 1+1=

I.1 ii.2 iii.3 iv.4 1+1=. i.1 ii.2 iii.3 iv.4 1+1=
Sarah N. Taylor, MD and Carol L Wagner, MD Department of Pediatrics

Sarah N. Taylor, MD and Carol L Wagner, MD Department of Pediatrics
Inhibition of CR HCT-116 (A and B) or CR HT-29 cells (B) xenografts in EPA and/or FuOx-treated SCID mice. Inhibition of CR HCT-116 (A and B) or CR HT-29.

Inhibition of CR HCT-116 (A and B) or CR HT-29 cells (B) xenografts in EPA and/or FuOx-treated SCID mice. Inhibition of CR HCT-116 (A and B) or CR HT-29.
25(OH)D and 1,25(OH)2D perfusion treatment effect on cancer-related markers: IF stains illustrating expression levels for Ki-67 (A), cyclin D1 (B), ErbB-2.

25(OH)D and 1,25(OH)2D perfusion treatment effect on cancer-related markers: IF stains illustrating expression levels for Ki-67 (A), cyclin D1 (B), ErbB-2.
Monthly rates of antibiotic administration.

Monthly rates of antibiotic administration.
Monthly rates of antibiotic administration.

Monthly rates of antibiotic administration.
Effect of plumbagin (PL) on the growth of prostate tumors in Pten-KO mice. Effect of plumbagin (PL) on the growth of prostate tumors in Pten-KO mice. A.

Effect of plumbagin (PL) on the growth of prostate tumors in Pten-KO mice. Effect of plumbagin (PL) on the growth of prostate tumors in Pten-KO mice. A.
Distribution of informative SNPs with LOH (black bars) on each chromosome (rows, oriented p-arm at the bottom and q-arm at the top of each chromosome)

Distribution of informative SNPs with LOH (black bars) on each chromosome (rows, oriented p-arm at the bottom and q-arm at the top of each chromosome)
ROC curve for separating advanced stages (advanced BE and EA) versus early stages (BE or BE instability) using total genome-wide LOH [area under the curve.

ROC curve for separating advanced stages (advanced BE and EA) versus early stages (BE or BE instability) using total genome-wide LOH [area under the curve.
Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late.

Number of 0.5-Mb windows with chromosome lesions that reached statistical significance across patients in early (BE early and BE instability) and late.
Expression changes of specific epigenetic-controlled tumor-related genes by the prenatal/maternal BSp treatment. qRT-PCR and Western blot analysis were.

Expression changes of specific epigenetic-controlled tumor-related genes by the prenatal/maternal BSp treatment. qRT-PCR and Western blot analysis were.
GLUT4 LXRE is required for downregulation of adipose GLUT4 mRNA during fasting and diet-induced obesity. GLUT4 LXRE is required for downregulation of adipose.

GLUT4 LXRE is required for downregulation of adipose GLUT4 mRNA during fasting and diet-induced obesity. GLUT4 LXRE is required for downregulation of adipose.
Gene expression of epigenetic modulators, HDAC1 and Dnmt1, and the histone acetylation modification patterns by the prenatal/maternal BSp dietary treatment.

Gene expression of epigenetic modulators, HDAC1 and Dnmt1, and the histone acetylation modification patterns by the prenatal/maternal BSp dietary treatment.
A1C (A) and serum glycated albumin (GA) (B) levels in 47 pregnant women (study 1) divided according to gestational period into group I (21–24 weeks; n.

A1C (A) and serum glycated albumin (GA) (B) levels in 47 pregnant women (study 1) divided according to gestational period into group I (21–24 weeks; n.
Dox administration was required for Tet-CD19CAR T cells to show a suppressive function against a CD19+ tumor in vivo. Dox administration was required for.

Dox administration was required for Tet-CD19CAR T cells to show a suppressive function against a CD19+ tumor in vivo. Dox administration was required for.
TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor tissues. TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor.

TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor tissues. TFAP2A is highly expressed in nasopharyngeal carcinoma cells and tumor.
Skin tumor size following ligand activation of PPARβ/δ and inhibition of COX2. Skin tumor size following ligand activation of PPARβ/δ and inhibition of.

Skin tumor size following ligand activation of PPARβ/δ and inhibition of COX2. Skin tumor size following ligand activation of PPARβ/δ and inhibition of.
Experimental schema. Experimental schema. Female C3 (1)/SV40 Tag mice were weaned from their mothers at 3 wk of age; behavior was assessed using a standard.

Experimental schema. Experimental schema. Female C3 (1)/SV40 Tag mice were weaned from their mothers at 3 wk of age; behavior was assessed using a standard.
Effects of AG on the colon histology score in the acute DSS colitis model. Effects of AG on the colon histology score in the acute DSS colitis model. Ten.

Effects of AG on the colon histology score in the acute DSS colitis model. Effects of AG on the colon histology score in the acute DSS colitis model. Ten.

Similar presentations

Ads by Google