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Marrick L. Kukin, MD  Mayo Clinic Proceedings 

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1 β-Blockers in Chronic Heart Failure: Considerations for Selecting an Agent 
Marrick L. Kukin, MD  Mayo Clinic Proceedings  Volume 77, Issue 11, Pages (November 2002) DOI: / Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Kaplan-Meier curve of cumulative percentage of total mortality (P>.001) in the Metoprolol CR/XL Randomized Intervention Trial in Congestive Heart Failure (MERIT-HF). P=.006 (adjusted); P>.001 (nominal). Reprinted with permission from Elsevier Science.5 Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Survival curve from the Cardiac Insufficiency Bisoprolol Study II (CIBIS-II) (P>.001). Reprinted with permission from Elsevier Science.4 Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 3 Kaplan-Meier analysis of survival from the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) trial (P=.001, adjusted). Reprinted with permission from Packer et al.7 Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2002 Mayo Foundation for Medical Education and Research Terms and Conditions


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