1. BioGRID: Biological General Repository for Interaction Datasets
Ben Bachman
Georgia Institute of Technology
28 June, 2006

2. Overview Database of protein-protein interactions Removes redundancies
Search protein of interest
Retrieve primary information
Physical and genetic interaction data
Links to other databases

3. Features Overview Realtime site statistics Can search an organism by
Genebank ID
Entrez-Gene ID
SGD ID
Gene name
Links to all known related enzymes
Links to information in other databases

4. Statistics

5. Search Criteria

6. Example Search

7. Example Results

8. Osprey Visualization tool Powered by BioGRID
Shows graphical relationships between proteins
Links to information included in BioGRID

9. Features Overview Add in known enzymes
Shows BioGRID data on the enzyme
Visualize links to related enzymes
Extended visualization
View information on relationship between enzymes
Links to database websites with more information

10. Osprey Example

11. Osprey Example

12. Osprey Example

13. Osprey Example

14. Osprey Example

15. Osprey Example

16. Summary
BioGRID sometimes lacking in information, but instead displays error message
Very well manicured database
Osprey could use a way to find the path between two enzymes
A few small UI problems
Many useful features